Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP90_RS00265 Genome accession   NZ_CP063124
Coordinates   54316..55539 (+) Length   407 a.a.
NCBI ID   WP_197559688.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C113_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 49316..60539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP90_RS00240 (INP90_00240) - 49901..50695 (-) 795 WP_197559685.1 sulfite exporter TauE/SafE family protein -
  INP90_RS00245 (INP90_00245) rppH 50695..51288 (-) 594 WP_049379955.1 RNA pyrophosphohydrolase -
  INP90_RS00250 (INP90_00250) ampD 51772..52335 (-) 564 WP_197559686.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP90_RS00255 (INP90_00255) pilA 52478..52921 (+) 444 WP_005697917.1 prepilin peptidase-dependent pilin Machinery gene
  INP90_RS00260 (INP90_00260) pilB 52928..54307 (+) 1380 WP_197559687.1 GspE/PulE family protein Machinery gene
  INP90_RS00265 (INP90_00265) pilC 54316..55539 (+) 1224 WP_197559688.1 type II secretion system F family protein Machinery gene
  INP90_RS00270 (INP90_00270) pilD 55536..56213 (+) 678 WP_197559689.1 prepilin peptidase Machinery gene
  INP90_RS00275 (INP90_00275) coaE 56299..56919 (+) 621 WP_197559690.1 dephospho-CoA kinase -
  INP90_RS00280 (INP90_00280) yacG 56912..57118 (+) 207 WP_005695505.1 DNA gyrase inhibitor YacG -
  INP90_RS00285 (INP90_00285) - 57115..57396 (+) 282 WP_197559691.1 GNAT family N-acetyltransferase -
  INP90_RS00290 (INP90_00290) rhlB 57487..58746 (+) 1260 WP_197559692.1 ATP-dependent RNA helicase RhlB -
  INP90_RS00295 (INP90_00295) mreD 58787..59275 (-) 489 WP_197559693.1 rod shape-determining protein MreD -
  INP90_RS00300 (INP90_00300) mreC 59275..60339 (-) 1065 WP_197559694.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46249.88 Da        Isoelectric Point: 9.7327

>NTDB_id=493189 INP90_RS00265 WP_197559688.1 54316..55539(+) (pilC) [Haemophilus parainfluenzae strain M1C113_1]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFLLIAKGFSHIRLQQDWQLNQKPKNAEISALLNQLSTLLSSAIPLKNA
LHILQDNCTQLGLHQWLGTLIELIESGLPFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSAELPTLTAVLLAMSQFLQHHFIALMIVCIFAIFMLKMALKHSLW
LNQKKNAMISRMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLQHIADNYQEKLNHKIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=493189 INP90_RS00265 WP_197559688.1 54316..55539(+) (pilC) [Haemophilus parainfluenzae strain M1C113_1]
ATGGCAAAGCAAAAACTCTTTTATTTTCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGCAGTCTGGTTGCCCAATC
TAAACAAGCCGCACAATTTCTGTTAATTGCAAAAGGTTTTAGCCACATTCGCTTGCAACAAGATTGGCAACTTAATCAGA
AACCTAAAAATGCTGAGATCAGTGCTTTATTAAATCAGCTATCTACACTACTCAGCTCTGCCATTCCATTAAAAAATGCA
TTACATATTTTGCAAGACAACTGCACACAATTGGGATTGCATCAGTGGCTTGGCACCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGCTTGGAAATTCAAGGAAAGTATTTAAATTTTCAAGAAATTCAACTTATTCAAGTGGGAGAGA
TGACAGGAAAACTGGCGGAGGTATGCACTAAAATTGCAGAACGTCGAACGCAATCATTAACGCTTCAACGAAAATTACAA
AAAATTATGCTTTATCCCGCCATGGTATTAGGTATTTCGCTTTCACTTACGTTGATTTTATTACTCTTCGTTGTACCACA
ATTTGCTGAAATGTATGGCGAAAACTCCGCTGAACTGCCTACATTAACTGCTGTGTTATTAGCCATGTCTCAATTCCTAC
AACATCATTTTATCGCCTTGATGATTGTCTGTATTTTCGCTATTTTTATGCTAAAGATGGCATTAAAACATTCTCTTTGG
CTAAATCAAAAAAAGAATGCGATGATTAGTCGCATGCCGATTTGGGGCAATATCATTTGCCTTTCTCGCTTAATCAGTTT
TAGCCATAACCTGCAATTAATGCTTCAATCTGGAGTGGCATTAACGCCTGCGCTAAATAGTTTTCTCCCCAAACAACAAA
CTTGGCAAACACAACGTACCTTAAAAGGTGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGTTATCCATTTTCAGAAAGTGTCAGTAGTCATCTTTTCCCAATGGAAGCACAACAAATGCTACAGATTGGAGAGAAAAG
TGGAAAACTTGCATTGATGTTGCAACATATTGCTGATAACTATCAAGAAAAGCTCAATCATAAAATCGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATCGGTATTATTATGATGGGCATGTATCTGCCGATTTTT
AATATGGGATCGGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.059

99.263

0.685
  pilC Haemophilus influenzae 86-028NP

68.317

99.263

0.678
  pilC Glaesserella parasuis strain SC1401

39.651

98.526

0.391