Detailed information NTG0493109

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: INP93_RS03635
• Genome accession: NZ_CP063121
• Coordinates: 736260..737642 (+)
• Length: 460 a.a.
• NCBI ID: WP_049369641.1
• Uniprot ID: -
• Organism: Haemophilus parainfluenzae strain M1C130_2
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 731260..742642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP93_RS09750	-	731271..731963 (-)	693	Protein_699	penicillin-binding protein 1A	-
INP93_RS03610 (INP93_03610)	-	732039..733889 (-)	1851	Protein_700	penicillin-binding protein 1A	-
INP93_RS03615 (INP93_03615)	-	733989..734837 (+)	849	WP_197545163.1	pilus assembly protein PilM	-
INP93_RS03620 (INP93_03620)	-	734824..735336 (+)	513	WP_197545164.1	PilN domain-containing protein	-
INP93_RS03625 (INP93_03625)	-	735333..735875 (+)	543	WP_049369637.1	hypothetical protein	-
INP93_RS03630 (INP93_03630)	-	735875..736258 (+)	384	WP_197545165.1	pilus assembly protein PilP	-
INP93_RS03635 (INP93_03635)	comE	736260..737642 (+)	1383	WP_049369641.1	type IV pilus secretin PilQ	Machinery gene
INP93_RS03640 (INP93_03640)	-	737662..738351 (+)	690	WP_049369643.1	ComF family protein	-
INP93_RS03645 (INP93_03645)	nfuA	738466..739050 (+)	585	WP_197545166.1	Fe-S biogenesis protein NfuA	-
INP93_RS03650 (INP93_03650)	comM	739094..740623 (-)	1530	WP_197545167.1	YifB family Mg chelatase-like AAA ATPase	Machinery gene
INP93_RS03655 (INP93_03655)	yihA	740753..741367 (-)	615	WP_065243638.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
INP93_RS03660 (INP93_03660)	-	741481..742350 (+)	870	WP_197545168.1	VirK/YbjX family protein	-

Sequence

Protein

• Length: 460 a.a.
• Molecular weight: 50967.58 Da
• Isoelectric Point: 7.5107

>NTDB_id=493109 INP93_RS03635 WP_049369641.1 736260..737642(+) (comE) [Haemophilus parainfluenzae strain M1C130_2]
MVKQKIKTKCGQFLMCFLILWTTYSAAENRVFSLRLKQAPMVATLQQVALEQNANLMIDDELEGTLSLQLDNVDFDRLLR
SVAKIKGLSFYQENNIYYLGKPSQHEQYAEKMTEPMAISGEGLPSETPLVSTTVKLHFAKASDVMKSLTTGSGSLLSPSG
TIAFDDRSNVLLIQDDARSVKNIKKLIAELDKPIEQIVIEARIVTITDESLKELGVRWGIFNPTEAAHRVGGSLDANGFS
NISNNLNVNFATTVTPAGSLALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTNGKNDT
QSVEFREAVLGLEVTPHISKDNNILLDLLVSQNSPGNRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKGV
DKVPLLGDIPGIKRLFSKESERHQKRELVIFVTPHILKQGERMEMAKKEKHFKQVEKVKK

Nucleotide

• Length: 1383 bp

>NTDB_id=493109 INP93_RS03635 WP_049369641.1 736260..737642(+) (comE) [Haemophilus parainfluenzae strain M1C130_2]
ATGGTAAAGCAGAAAATAAAAACAAAGTGCGGTCAGTTTTTAATGTGTTTTTTGATCCTATGGACAACGTACTCAGCGGC
AGAAAATCGCGTCTTTTCACTTCGATTAAAACAGGCGCCAATGGTAGCAACTCTCCAGCAGGTTGCTCTTGAGCAAAATG
CCAATTTAATGATTGATGATGAGCTAGAAGGAACGCTTTCATTGCAATTAGATAACGTGGATTTTGATCGTTTATTGCGT
TCTGTGGCAAAAATCAAAGGGCTCTCTTTTTATCAAGAAAATAATATTTATTATTTGGGTAAGCCTTCTCAACATGAACA
ATATGCAGAGAAAATGACAGAACCTATGGCAATTAGCGGAGAAGGTTTGCCTAGTGAAACACCACTTGTGAGTACAACGG
TTAAACTGCATTTTGCCAAGGCCTCTGATGTGATGAAATCTTTAACAACTGGTAGTGGTTCTTTGCTTTCACCTAGCGGC
ACGATTGCATTTGATGACCGAAGCAATGTATTACTGATTCAGGATGATGCACGTTCTGTCAAAAATATCAAAAAGTTAAT
CGCAGAGTTGGATAAACCCATTGAGCAAATCGTGATTGAGGCACGTATTGTGACGATTACTGATGAAAGCCTAAAAGAAT
TAGGTGTGCGTTGGGGCATTTTTAATCCTACTGAGGCAGCCCATCGAGTGGGTGGCAGTTTAGATGCGAACGGGTTTAGC
AATATCAGTAATAATTTAAATGTGAATTTTGCGACAACGGTCACGCCAGCTGGCTCATTAGCTCTTCAAGTAGCTAAAAT
TAATGGTCGATTATTAGACCTAGAATTGACCGCACTTGAACGTGAAAATAACGTAGAAATTATTGCAAGCCCTCGCTTAC
TTACTACCAACAAGAAAAGCGCAAGCATCAAACAAGGGACAGAAATTCCTTATGTGGTGACAAATGGGAAAAATGACACT
CAATCAGTGGAATTTCGAGAAGCGGTGTTGGGATTAGAAGTGACACCACATATTTCGAAGGATAATAATATTTTATTGGA
TTTATTAGTGAGTCAAAATTCTCCAGGGAATCGAGTGGCTTATGGGCAAAATGAAGTGGTATCCATTGATAAACAAGAAA
TTAATACGCAAGTGTTTGCCAAAGATGGCGAAACAATTGTATTAGGTGGTGTATTTCACGATACGATCACGAAAGGTGTC
GATAAAGTACCATTATTGGGCGATATTCCAGGTATTAAGCGCTTATTTAGTAAGGAAAGTGAACGTCATCAAAAACGCGA
ACTCGTCATTTTTGTGACACCTCATATTTTAAAACAAGGTGAAAGAATGGAAATGGCTAAGAAAGAAAAGCATTTTAAGC
AAGTTGAAAAAGTGAAAAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (133-196)

• Bacterial type II and III secretion system protein (Secretin) (278-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	73.274	97.609	0.715
comE	Haemophilus influenzae 86-028NP	72.383	97.609	0.707
comE	Glaesserella parasuis strain SC1401	54.137	91.957	0.498
pilQ	Vibrio campbellii strain DS40M4	41.667	93.913	0.391
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	42.217	92.174	0.389
pilQ	Vibrio cholerae strain A1552	42.217	92.174	0.389