Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP93_RS00265 Genome accession   NZ_CP063121
Coordinates   53958..55181 (+) Length   407 a.a.
NCBI ID   WP_197544814.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C130_2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48958..60181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP93_RS00240 (INP93_00240) - 49543..50337 (-) 795 WP_197544810.1 sulfite exporter TauE/SafE family protein -
  INP93_RS00245 (INP93_00245) rppH 50337..50930 (-) 594 WP_049379955.1 RNA pyrophosphohydrolase -
  INP93_RS00250 (INP93_00250) ampD 51414..51977 (-) 564 WP_197544811.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP93_RS00255 (INP93_00255) pilA 52120..52563 (+) 444 WP_197544812.1 prepilin peptidase-dependent pilin Machinery gene
  INP93_RS00260 (INP93_00260) pilB 52570..53949 (+) 1380 WP_197544813.1 GspE/PulE family protein Machinery gene
  INP93_RS00265 (INP93_00265) pilC 53958..55181 (+) 1224 WP_197544814.1 type II secretion system F family protein Machinery gene
  INP93_RS00270 (INP93_00270) pilD 55178..55855 (+) 678 WP_197544815.1 prepilin peptidase Machinery gene
  INP93_RS00275 (INP93_00275) coaE 55944..56564 (+) 621 WP_197544816.1 dephospho-CoA kinase -
  INP93_RS00280 (INP93_00280) yacG 56557..56763 (+) 207 WP_197544817.1 DNA gyrase inhibitor YacG -
  INP93_RS00285 (INP93_00285) - 56760..57041 (+) 282 WP_197544818.1 GNAT family N-acetyltransferase -
  INP93_RS00290 (INP93_00290) rhlB 57132..58394 (+) 1263 WP_197544819.1 ATP-dependent RNA helicase RhlB -
  INP93_RS00295 (INP93_00295) mreD 58436..58924 (-) 489 WP_193451403.1 rod shape-determining protein MreD -
  INP93_RS00300 (INP93_00300) mreC 58924..59988 (-) 1065 WP_197544820.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46332.99 Da        Isoelectric Point: 9.6100

>NTDB_id=493095 INP93_RS00265 WP_197544814.1 53958..55181(+) (pilC) [Haemophilus parainfluenzae strain M1C130_2]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFQLIAKGFNHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNT
LHILQDNCSQLGLHEWLGALIELIESGLPFSQSLEMQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSAELPILTAVLLAMSQFLQHHFIALMIVCIFALFMLKMALKHSLW
LNQKKNALISRMPIWGNIICLSRLISFSHNLQLMLQSGVALMPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=493095 INP93_RS00265 WP_197544814.1 53958..55181(+) (pilC) [Haemophilus parainfluenzae strain M1C130_2]
ATGGCAAAGCAAAAACTCTTTTATTTTCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGCAGTCTTGTTGCCCAATC
TAAACAAGCTGCACAATTCCAGTTAATCGCAAAAGGTTTTAATCACATTCGCTTACAACAAGATTGGCAACTTAATCAGA
AACCGAAAAATGCAGAAATCAGTGCTTTATTGAATCAACTGGCTACATTACTCAGTTCAGCCATTCCATTAAAGAATACA
TTACATATTTTGCAAGATAACTGCTCGCAATTGGGATTGCATGAGTGGCTTGGCGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGTTTGGAAATGCAAGGAAAGTATTTAAATTTTCAAGAAATTCAACTTATTCAAGTGGGAGAAA
TGACCGGAAAACTGGCGGAGGTATGCACTAAAATTGCAGAACGTCGAACACAATCATTAACGCTTCAACGCAAATTGCAA
AAAATTATGCTTTATCCTGCCATGGTATTAGGTATTTCGCTTTCACTTACGTTGATTTTATTACTCTTTGTTGTACCACA
ATTTGCTGAAATGTATGGCGAAAACTCAGCTGAGCTACCTATATTGACTGCCGTATTATTAGCCATGTCTCAATTCCTAC
AACATCATTTTATCGCCTTGATGATTGTCTGCATTTTCGCTCTTTTTATGCTAAAGATGGCATTAAAACATTCTCTTTGG
CTAAATCAAAAAAAGAATGCGCTGATTAGTCGCATGCCAATTTGGGGCAATATCATTTGCCTTTCTCGTCTAATCAGTTT
TAGTCATAACTTACAATTAATGCTTCAATCCGGTGTAGCATTAATGCCTGCGCTAAATAGTTTTCTCCCCAAACAACAAA
CCTGGCAAACACAACGTACCTTAAAAGGCGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGTTATCCATTTTCAGAAAGTGTCAGTAGTCATCTTTTCCCAATGGAAGCACAACAAATGCTACAGATTGGAGAGAAAAG
TGGAAAACTTGCGTTGATGTTGCGTCATATTGCTGATAACTATCAAGAAAAACTCAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATTGGTATTATTATGATGGGCATGTATCTGCCGATTTTT
AATATGGGATCGGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.802

99.263

0.693
  pilC Haemophilus influenzae 86-028NP

68.812

99.263

0.683
  pilC Glaesserella parasuis strain SC1401

39.651

98.526

0.391