Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP99_RS00265 Genome accession   NZ_CP063111
Coordinates   53386..54609 (+) Length   407 a.a.
NCBI ID   WP_197542328.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C152_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48386..59609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP99_RS00240 (INP99_00240) - 48968..49762 (-) 795 WP_177989464.1 sulfite exporter TauE/SafE family protein -
  INP99_RS00245 (INP99_00245) rppH 49762..50355 (-) 594 WP_178160903.1 RNA pyrophosphohydrolase -
  INP99_RS00250 (INP99_00250) ampD 50840..51403 (-) 564 WP_054419755.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP99_RS00255 (INP99_00255) pilA 51548..51991 (+) 444 WP_005697917.1 prepilin peptidase-dependent pilin Machinery gene
  INP99_RS00260 (INP99_00260) pilB 51998..53377 (+) 1380 WP_197542327.1 GspE/PulE family protein Machinery gene
  INP99_RS00265 (INP99_00265) pilC 53386..54609 (+) 1224 WP_197542328.1 type II secretion system F family protein Machinery gene
  INP99_RS00270 (INP99_00270) pilD 54606..55283 (+) 678 WP_197542329.1 prepilin peptidase Machinery gene
  INP99_RS00275 (INP99_00275) coaE 55371..55991 (+) 621 WP_197542330.1 dephospho-CoA kinase -
  INP99_RS00280 (INP99_00280) yacG 55984..56190 (+) 207 WP_005695505.1 DNA gyrase inhibitor YacG -
  INP99_RS00285 (INP99_00285) - 56187..56468 (+) 282 WP_178160891.1 GNAT family N-acetyltransferase -
  INP99_RS00290 (INP99_00290) rhlB 56559..57818 (+) 1260 WP_197542331.1 ATP-dependent RNA helicase RhlB -
  INP99_RS00295 (INP99_00295) mreD 57860..58348 (-) 489 WP_111327318.1 rod shape-determining protein MreD -
  INP99_RS00300 (INP99_00300) mreC 58348..59412 (-) 1065 WP_070582548.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46312.91 Da        Isoelectric Point: 9.7422

>NTDB_id=492906 INP99_RS00265 WP_197542328.1 53386..54609(+) (pilC) [Haemophilus parainfluenzae strain M1C152_1]
MAKQKLFYFQAYDQRQQWQKGSLIAQSKQAAQFLLIAKGFSHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCTQLGLHQWLSALIELIESGLPFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSAELPTLTAVLLAMSQFLQHHFISLMIVCIFVIFMLKISLKHSLW
LNQKKNALVNRMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=492906 INP99_RS00265 WP_197542328.1 53386..54609(+) (pilC) [Haemophilus parainfluenzae strain M1C152_1]
ATGGCAAAGCAAAAACTCTTTTATTTCCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGCAGCCTTATTGCTCAATC
TAAACAAGCCGCACAATTTCTGTTAATTGCAAAAGGTTTTAGTCACATTCGCTTGCAACAAGATTGGCAACTTAATCAGA
AACCGAAAAATGCAGAAATCAGTGCTTTATTGAATCAACTGGCTACATTGCTCAGTTCTGCCATTCCATTAAAAAATGCA
TTACATATTTTGCAAGACAACTGCACACAATTGGGTTTGCATCAGTGGCTTAGCGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGCTTGGAAATACAAGGAAAGTATTTAAACTTTCAAGAGATTCAACTTATTCAAGTGGGAGAAA
TGACAGGAAAACTGGCAGAGGTATGCACTAAAATTGCAGAACGTCGAACGCAATCATTAACGCTTCAACGCAAATTGCAA
AAAATTATGCTTTATCCTGCCATGGTATTAGGTATTTCGCTTTCACTTACGTTGATTTTATTACTCTTCGTTGTACCGCA
ATTTGCTGAAATGTATGGCGAAAATTCCGCTGAATTGCCTACATTGACTGCCGTATTATTAGCCATGTCCCAATTCCTAC
AACATCATTTTATTTCATTGATGATTGTCTGTATTTTCGTTATTTTTATGCTGAAGATCTCATTAAAACATTCCCTTTGG
CTGAATCAAAAAAAGAATGCGCTAGTTAATCGTATGCCGATTTGGGGCAATATCATTTGCCTTTCTCGTTTAATCAGTTT
TAGCCATAACCTGCAATTAATGCTTCAATCCGGAGTGGCATTAACGCCTGCGTTAAATAGCTTCCTCCCAAAACAACAAA
CCTGGCAAACACAACGTACCTTAAAAGGTGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGTTATCCGTTTTCGGAGAGTGTCAGTAGCCATCTTTTCCCAATGGAAGCACAACAAATGCTACAGATTGGAGAAAAAAG
TGGAAAACTTGCGTTGATGTTGCGTCATATTGCTGATAACTATCAAGAAAAGCTCAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATCGGTATTATTATGATGGGCATGTATCTGCCGATTTTT
AATATGGGATCCGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.554

99.263

0.69
  pilC Haemophilus influenzae 86-028NP

68.812

99.263

0.683
  pilC Glaesserella parasuis strain SC1401

39.9

98.526

0.393