Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   INQ00_RS03760 Genome accession   NZ_CP063110
Coordinates   758040..759422 (+) Length   460 a.a.
NCBI ID   WP_197547336.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C160_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 753040..764422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INQ00_RS03735 (INQ00_03740) - 753057..755669 (-) 2613 WP_197547333.1 penicillin-binding protein 1A -
  INQ00_RS03740 (INQ00_03745) - 755769..756611 (+) 843 WP_197547334.1 competence protein ComA -
  INQ00_RS03745 (INQ00_03750) - 756604..757116 (+) 513 WP_054420356.1 hypothetical protein -
  INQ00_RS03750 (INQ00_03755) - 757113..757655 (+) 543 WP_054420357.1 hypothetical protein -
  INQ00_RS03755 (INQ00_03760) - 757655..758038 (+) 384 WP_197547335.1 pilus assembly protein PilP -
  INQ00_RS03760 (INQ00_03765) comE 758040..759422 (+) 1383 WP_197547336.1 type IV pilus secretin PilQ Machinery gene
  INQ00_RS03765 (INQ00_03770) - 759443..760132 (+) 690 WP_197547337.1 ComF family protein -
  INQ00_RS03770 (INQ00_03775) nfuA 760246..760830 (+) 585 WP_014064659.1 Fe-S biogenesis protein NfuA -
  INQ00_RS03775 (INQ00_03780) comM 760874..762403 (-) 1530 WP_070776023.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  INQ00_RS03780 (INQ00_03785) yihA 762533..763147 (-) 615 WP_197547338.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  INQ00_RS03785 (INQ00_03790) - 763261..764130 (+) 870 WP_197547339.1 VirK/YbjX family protein -

Sequence

Protein


Download         Length: 460 a.a.        Molecular weight: 51119.79 Da        Isoelectric Point: 7.5107

>NTDB_id=492889 INQ00_RS03760 WP_197547336.1 758040..759422(+) (comE) [Haemophilus parainfluenzae strain M1C160_1]
MIKQKIKTKCGQFLMCFLILWTTYSAAENRVFSLRLKQAPMVATLQQLALEQNANLMIDDELEGTLSLQLENVDFDRLLR
SVAKIKGLSFYQENNIYYLGKPSQHEQYAEKMTEPMAISGESLSSETPLVSTTIKLHFAKASDVMKSLTTGSGSLLSPSG
TITFDDRSNVLLIQDDARSVKNIKKLIAELDKPIEQIVIEARIVTITDESLKELGVRWGIFNPTEAAHRVSGSLDANGFS
NISNNLNVNFATMVTPAGSLALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTNGKNDT
QSVEFREAVLGLEVTPHISKDNNILLDLLVSQNSPGNRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKGV
DKVPLLGDIPGIKRLFSKESERHQKRELVIFVTPHILKQGERMEMAKKEKHFKQIEKAKK

Nucleotide


Download         Length: 1383 bp        

>NTDB_id=492889 INQ00_RS03760 WP_197547336.1 758040..759422(+) (comE) [Haemophilus parainfluenzae strain M1C160_1]
ATGATAAAGCAGAAAATAAAAACAAAGTGCGGTCAGTTTTTAATGTGTTTTTTGATCCTATGGACAACCTACTCAGCGGC
AGAGAATCGCGTATTTTCACTTCGCTTAAAGCAAGCTCCCATGGTGGCGACACTCCAACAACTTGCTCTTGAGCAAAATG
CTAATTTAATGATTGATGATGAGCTAGAAGGAACGCTTTCATTACAATTAGAGAACGTAGATTTTGATCGTTTATTGCGT
TCTGTCGCAAAAATCAAAGGGCTCTCTTTTTATCAAGAAAATAATATTTATTATTTGGGTAAGCCTTCTCAACATGAACA
ATATGCAGAGAAAATGACAGAACCGATGGCAATTAGCGGGGAAAGTTTGTCTAGTGAAACACCACTTGTGAGTACAACGA
TTAAACTGCATTTTGCTAAGGCCTCTGATGTGATGAAATCTTTAACAACAGGGAGCGGTTCTTTGCTTTCACCTAGCGGC
ACAATTACATTTGATGATCGAAGCAATGTGTTACTGATTCAGGATGATGCACGTTCTGTCAAAAATATCAAAAAATTAAT
TGCAGAACTGGATAAACCCATTGAACAAATTGTCATTGAAGCACGTATTGTGACGATTACTGATGAAAGCCTGAAAGAGT
TAGGTGTACGTTGGGGCATTTTTAATCCTACTGAGGCTGCCCATAGAGTGAGTGGCAGTCTAGATGCAAATGGCTTTAGT
AATATCAGTAATAATTTAAACGTGAATTTTGCGACAATGGTCACGCCAGCTGGCTCATTAGCACTTCAAGTGGCTAAAAT
TAATGGCCGATTATTAGACTTAGAATTAACCGCACTTGAACGTGAAAATAACGTAGAAATTATTGCAAGCCCTCGCTTAC
TTACGACCAACAAGAAAAGTGCAAGCATCAAACAAGGGACAGAAATTCCTTATGTGGTGACGAATGGGAAAAATGATACA
CAGTCAGTAGAGTTTCGCGAGGCTGTCTTAGGATTGGAAGTCACTCCGCATATTTCTAAGGATAATAATATCTTATTGGA
TTTATTAGTCAGTCAAAATTCCCCGGGTAATCGCGTGGCTTACGGGCAAAATGAAGTGGTATCCATTGATAAACAGGAAA
TTAATACGCAAGTTTTTGCCAAAGATGGCGAAACAATTGTATTGGGTGGTGTATTCCACGATACGATCACGAAAGGTGTC
GATAAAGTACCATTATTGGGCGATATTCCAGGTATTAAACGCTTATTTAGTAAGGAAAGCGAACGTCATCAAAAGCGAGA
GCTTGTAATTTTTGTGACCCCTCATATTTTGAAACAAGGTGAAAGAATGGAAATGGCTAAGAAAGAAAAGCATTTTAAGC
AAATTGAAAAAGCGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(278-438)

Bacterial type II/III secretion system short domain (Secretin_N)

(133-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

73.274

97.609

0.715
  comE Haemophilus influenzae 86-028NP

72.383

97.609

0.707
  comE Glaesserella parasuis strain SC1401

54.137

91.957

0.498
  pilQ Vibrio campbellii strain DS40M4

41.57

94.13

0.391
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.745

92.174

0.385
  pilQ Vibrio cholerae strain A1552

41.745

92.174

0.385