Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KHZ70_RS23675 Genome accession   NZ_CP074576
Coordinates   4898525..4899649 (+) Length   374 a.a.
NCBI ID   WP_000228527.1    Uniprot ID   -
Organism   Escherichia coli strain CS18F     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 4893525..4904649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KHZ70_RS23650 (KHZ70_23655) mscL 4893651..4894061 (-) 411 WP_000022444.1 large-conductance mechanosensitive channel protein MscL -
  KHZ70_RS23655 (KHZ70_23660) trkA 4894191..4895567 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  KHZ70_RS23660 (KHZ70_23665) rsmB 4895589..4896878 (-) 1290 WP_001318069.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KHZ70_RS23665 (KHZ70_23670) fmt 4896924..4897871 (-) 948 WP_000004420.1 methionyl-tRNA formyltransferase -
  KHZ70_RS23670 (KHZ70_23675) def 4897886..4898395 (-) 510 WP_000114986.1 peptide deformylase -
  KHZ70_RS23675 (KHZ70_23680) dprA 4898525..4899649 (+) 1125 WP_000228527.1 DNA-protecting protein DprA Machinery gene
  KHZ70_RS23680 (KHZ70_23685) smg 4899621..4900094 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  KHZ70_RS23685 (KHZ70_23690) yrdD 4900123..4900665 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  KHZ70_RS23690 (KHZ70_23695) tsaC 4900670..4901242 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  KHZ70_RS23695 (KHZ70_23700) aroE 4901247..4902065 (+) 819 WP_000451227.1 shikimate dehydrogenase -
  KHZ70_RS23700 (KHZ70_23705) yrdB 4902062..4902319 (+) 258 WP_001070566.1 DUF1488 domain-containing protein -
  KHZ70_RS23705 (KHZ70_23710) yrdA 4902295..4902849 (-) 555 WP_001318068.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40982.87 Da        Isoelectric Point: 6.2662

>NTDB_id=491665 KHZ70_RS23675 WP_000228527.1 4898525..4899649(+) (dprA) [Escherichia coli strain CS18F]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLSDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=491665 KHZ70_RS23675 WP_000228527.1 4898525..4899649(+) (dprA) [Escherichia coli strain CS18F]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGTGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCTCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGTCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Legionella pneumophila strain ERS1305867

43.658

90.642

0.396
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396