Detailed information NTG0049054

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: SESEC_RS05045
• Genome accession: NC_017582
• Coordinates: 1061773..1062510 (+)
• Length: 245 a.a.
• NCBI ID: WP_014622844.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus ATCC 35246
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1056773..1067510

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SESEC_RS05015 (SeseC_01255)	-	1057218..1058123 (-)	906	WP_012677986.1	diacylglycerol/lipid kinase family protein	-
SESEC_RS05020 (SeseC_01256)	trhA	1058233..1058883 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
SESEC_RS05025 (SeseC_01257)	-	1058867..1059322 (-)	456	WP_014622841.1	DUF1836 domain-containing protein	-
SESEC_RS05030 (SeseC_01258)	-	1059582..1060337 (+)	756	WP_014622842.1	class I SAM-dependent methyltransferase	-
SESEC_RS05035 (SeseC_01259)	-	1060365..1060703 (+)	339	WP_014622843.1	cupin domain-containing protein	-
SESEC_RS05040 (SeseC_01260)	-	1060705..1061010 (+)	306	WP_012677981.1	AraC family ligand binding domain-containing protein	-
SESEC_RS05045 (SeseC_01261)	comE/blpR	1061773..1062510 (+)	738	WP_014622844.1	response regulator transcription factor	Regulator
SESEC_RS05050	-	1062883..1063083 (+)	201	WP_012679509.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SESEC_RS05055 (SeseC_01262)	-	1063150..1064004 (+)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
SESEC_RS05060 (SeseC_01263)	-	1064010..1065173 (+)	1164	WP_014622845.1	ABC transporter permease subunit	-
SESEC_RS05065 (SeseC_01264)	-	1065435..1065665 (+)	231	WP_012515596.1	Blp family class II bacteriocin	-
SESEC_RS10410	-	1066535..1066816 (+)	282	WP_080004977.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28903.28 Da
• Isoelectric Point: 8.2679

>NTDB_id=49054 SESEC_RS05045 WP_014622844.1 1061773..1062510(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
MNIFILEDDLGQQFRLQMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHRLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKLKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=49054 SESEC_RS05045 WP_014622844.1 1061773..1062510(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTCAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATTGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAGGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAACGGGCAGTCTTGCATGGTTTCAAGACTAAAACTGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (16-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.306	98.776	0.527
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367