Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SESEC_RS04840 Genome accession   NC_017582
Coordinates   1021584..1022894 (+) Length   436 a.a.
NCBI ID   WP_014622812.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus ATCC 35246     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1016584..1027894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SESEC_RS04825 (SeseC_01209) phoU 1017075..1017728 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  SESEC_RS04830 (SeseC_01210) - 1017962..1020499 (+) 2538 WP_014622811.1 M1 family metallopeptidase -
  SESEC_RS04835 (SeseC_01211) ciaR 1020917..1021591 (+) 675 WP_012515548.1 response regulator transcription factor Regulator
  SESEC_RS04840 (SeseC_01212) ciaH 1021584..1022894 (+) 1311 WP_014622812.1 sensor histidine kinase Regulator
  SESEC_RS04845 (SeseC_01214) - 1023278..1023712 (+) 435 WP_012678015.1 hypothetical protein -
  SESEC_RS10735 (SeseC_01215) - 1023794..1023970 (+) 177 WP_014622814.1 hypothetical protein -
  SESEC_RS04850 (SeseC_01216) - 1023986..1024393 (+) 408 WP_014622815.1 hypothetical protein -
  SESEC_RS04855 (SeseC_01217) - 1024403..1024693 (+) 291 WP_014622816.1 hypothetical protein -
  SESEC_RS04860 (SeseC_01218) - 1024617..1025000 (+) 384 WP_038674323.1 hypothetical protein -
  SESEC_RS04865 (SeseC_01219) - 1025002..1025253 (+) 252 WP_014622818.1 hypothetical protein -
  SESEC_RS04870 (SeseC_01220) - 1025269..1025688 (+) 420 WP_014622819.1 hypothetical protein -
  SESEC_RS04875 (SeseC_01221) - 1025858..1026184 (+) 327 WP_014622820.1 hypothetical protein -
  SESEC_RS04880 (SeseC_01222) - 1026186..1027409 (+) 1224 WP_014622821.1 hypothetical protein -
  SESEC_RS04885 (SeseC_01223) - 1027406..1027798 (+) 393 WP_012677439.1 hypothetical protein -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49604.24 Da        Isoelectric Point: 9.6507

>NTDB_id=49053 SESEC_RS04840 WP_014622812.1 1021584..1022894(+) (ciaH) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=49053 SESEC_RS04840 WP_014622812.1 1021584..1022894(+) (ciaH) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCTAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACCACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTTCACATCAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAACTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCACTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACCACTAATTTGTTAAACCTAGCGAGACGTGATGATGGCATTAAGCCGCAGCTGGTTGATGTTG
ATGCAGCATTTTTTGACACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGTACCATATTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.606

100

0.516
  ciaH Streptococcus pneumoniae D39

51.606

100

0.516
  ciaH Streptococcus pneumoniae R6

51.606

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.606

100

0.516

Multiple sequence alignment