Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   SESEC_RS02555 Genome accession   NC_017582
Coordinates   526329..527696 (+) Length   455 a.a.
NCBI ID   WP_012515170.1    Uniprot ID   A0AAW3GNZ0
Organism   Streptococcus equi subsp. zooepidemicus ATCC 35246     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 523451..532542 526329..527696 within 0


Gene organization within MGE regions


Location: 523451..532542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SESEC_RS02545 (SeseC_00629) tnpA 523451..523924 (+) 474 WP_014622411.1 IS200/IS605 family transposase -
  SESEC_RS02550 comA 524159..526314 (+) 2156 Protein_476 peptide cleavage/export ABC transporter ComA -
  SESEC_RS02555 (SeseC_00632) comB 526329..527696 (+) 1368 WP_012515170.1 bacteriocin secretion accessory protein Regulator
  SESEC_RS02560 (SeseC_00634) nrdF 528897..529910 (+) 1014 WP_012678369.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
  SESEC_RS02565 (SeseC_00635) nrdI 529912..530322 (+) 411 WP_014622448.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  SESEC_RS02570 (SeseC_00636) nrdE 530368..532542 (+) 2175 WP_014622449.1 class 1b ribonucleoside-diphosphate reductase subunit alpha -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50812.92 Da        Isoelectric Point: 5.1918

>NTDB_id=49042 SESEC_RS02555 WP_012515170.1 526329..527696(+) (comB) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
MNNNILESAEFYNRRYHNFSSRVILPTLLLFLFGVFFLAFAKKEISIISTATVEPNIILSNIQSTSNNTILTNNLKDNKY
VKFGDLLIKYDSRKEGIQQETYQTQLNNLQIQKEQLELLKASIEAGNSQFPEKDNYGYYQTFIDYLNQINTLSANVNQQN
ENVSSQNTAASNQQVEIENAIKGLTSQISDYQSVRSAIQNGTVVDLDNRAYSIYRSYLTQTSSLVDNTDKTAVINQFVAQ
IDSQINQLESSVAGYRIQHAGSGVQQSYSSTLESQLASLKAQSITKVEQELSALSNQITELEGTNKLQKNTSSKTSIVAN
EDGVLHLNQEFIGANIVPEGTIFAQVYPEMKKGTVVKITGYLPSTEISSISIGDTARFSTKDDNGETLDLIVKLSSIDNA
ATKTKNGNYFKVESKLQLKEKEAQLLKYGLEGKFILITGTKSYLNYYIDKFIGEK

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=49042 SESEC_RS02555 WP_012515170.1 526329..527696(+) (comB) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
ATGAATAACAATATATTAGAAAGTGCGGAATTTTATAACCGTCGTTACCACAACTTTTCTAGTCGTGTCATTCTACCTAC
TTTGCTGCTTTTCTTGTTTGGTGTTTTCTTCCTAGCATTTGCAAAGAAAGAAATTTCTATTATTTCAACTGCAACAGTTG
AACCAAATATAATTCTTTCCAATATTCAATCTACAAGTAATAATACAATATTAACCAATAATCTAAAAGATAATAAATAT
GTCAAATTTGGAGACTTATTGATAAAATATGATTCAAGAAAAGAAGGTATTCAACAAGAGACCTATCAAACTCAATTAAA
TAATTTACAAATCCAAAAAGAACAGTTAGAGCTATTAAAAGCAAGTATTGAAGCTGGAAACAGTCAATTTCCAGAAAAAG
ATAATTATGGATATTATCAAACATTTATTGACTACTTAAATCAGATAAACACCTTATCAGCCAATGTAAATCAGCAAAAT
GAAAATGTCTCTTCACAAAATACTGCAGCTAGCAATCAGCAAGTAGAAATTGAGAATGCCATCAAAGGTCTCACAAGTCA
AATTTCAGATTATCAATCTGTTCGCTCGGCGATTCAAAATGGAACAGTGGTAGATCTTGATAATCGGGCTTATTCTATCT
ATAGGAGTTATCTAACTCAAACATCGAGTTTGGTAGATAATACTGATAAAACCGCTGTTATTAATCAATTTGTTGCTCAA
ATTGATAGTCAGATCAATCAACTAGAGAGTAGTGTAGCTGGTTATCGGATTCAGCATGCTGGTTCAGGAGTGCAACAATC
TTACTCTTCAACTCTAGAGAGTCAACTGGCTTCCTTAAAAGCGCAAAGCATAACCAAAGTTGAGCAAGAGTTGTCTGCTT
TGTCGAATCAAATTACAGAATTAGAGGGAACAAATAAACTTCAGAAGAACACATCATCTAAGACCTCTATAGTTGCCAAT
GAAGATGGTGTGTTGCATCTTAATCAGGAATTTATTGGTGCAAATATTGTTCCTGAAGGAACAATATTTGCTCAAGTTTA
TCCAGAAATGAAAAAAGGAACTGTTGTAAAAATCACAGGTTATTTACCTTCGACGGAAATATCAAGTATTTCTATTGGAG
ATACAGCACGATTTTCCACGAAAGATGATAATGGCGAAACTCTTGATTTAATAGTTAAATTATCTAGTATTGACAATGCT
GCAACTAAAACAAAAAATGGGAATTATTTTAAAGTTGAATCTAAGTTACAGCTTAAAGAAAAAGAAGCTCAATTATTGAA
ATATGGGCTTGAGGGTAAATTTATTTTAATTACGGGAACAAAAAGTTACTTGAATTACTATATTGATAAATTTATCGGTG
AGAAGTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(317-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

50.221

99.341

0.499
  comB Streptococcus pneumoniae D39

50.221

99.341

0.499
  comB Streptococcus pneumoniae R6

50.221

99.341

0.499
  comB Streptococcus pneumoniae TIGR4

49.336

99.341

0.49
  comB Streptococcus mitis NCTC 12261

49.115

99.341

0.488
  comB Streptococcus mitis SK321

48.894

99.341

0.486
  comB Streptococcus gordonii str. Challis substr. CH1

47.894

99.121

0.475

Multiple sequence alignment