NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	KFU67_RS02640	Genome accession	NZ_CP074031
Coordinates	542584..543708 (+)	Length	374 a.a.
NCBI ID	WP_000228525.1	Uniprot ID	-
Organism	Escherichia coli strain PK12
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 537584..548708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFU67_RS02615 (KFU67_02570)	mscL	537710..538120 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
KFU67_RS02620 (KFU67_02575)	trkA	538250..539626 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
KFU67_RS02625 (KFU67_02580)	rsmB	539648..540937 (-)	1290	WP_001361938.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
KFU67_RS02630 (KFU67_02585)	fmt	540983..541930 (-)	948	WP_000004466.1	methionyl-tRNA formyltransferase	-
KFU67_RS02635 (KFU67_02590)	def	541945..542454 (-)	510	WP_000114986.1	peptide deformylase	-
KFU67_RS02640 (KFU67_02595)	dprA	542584..543708 (+)	1125	WP_000228525.1	DNA-protecting protein DprA	Machinery gene
KFU67_RS02645 (KFU67_02600)	smg	543680..544153 (+)	474	WP_000460682.1	DUF494 family protein Smg	-
KFU67_RS02650 (KFU67_02605)	yrdD	544182..544724 (+)	543	WP_001129723.1	type I DNA topoisomerase	-
KFU67_RS02655 (KFU67_02610)	tsaC	544729..545301 (+)	573	WP_001361937.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
KFU67_RS02660 (KFU67_02615)	aroE	545306..546124 (+)	819	WP_000451226.1	shikimate dehydrogenase	-
KFU67_RS02665 (KFU67_02620)	yrdB	546121..546378 (+)	258	WP_001070584.1	DUF1488 domain-containing protein	-
KFU67_RS02670 (KFU67_02625)	yrdA	546354..546908 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40933.83 Da Isoelectric Point: 6.1402

                                >NTDB_id=490182 KFU67_RS02640 WP_000228525.1 542584..543708(+) (dprA) [Escherichia coli strain PK12]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHAPLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=490182 KFU67_RS02640 WP_000228525.1 542584..543708(+) (dprA) [Escherichia coli strain PK12]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCTCCACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Legionella pneumophila strain ERS1305867	43.363	90.642	0.393
dprA	Haemophilus influenzae Rd KW20	43.62	90.107	0.393

Detailed information NTG0490182