Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SGGB_RS01950 Genome accession   NC_017576
Coordinates   351318..352073 (+) Length   251 a.a.
NCBI ID   WP_009853397.1    Uniprot ID   A0A060RH68
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 346318..357073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS01935 (SGGB_0341) - 346727..348298 (-) 1572 WP_009853395.1 ABC transporter permease subunit -
  SGGB_RS01940 (SGGB_0342) - 348431..350326 (+) 1896 WP_009853396.1 DUF2207 domain-containing protein -
  SGGB_RS01945 (SGGB_0343) - 350378..351217 (+) 840 WP_013642683.1 undecaprenyl-diphosphate phosphatase -
  SGGB_RS01950 (SGGB_0344) mecA 351318..352073 (+) 756 WP_009853397.1 adaptor protein MecA Regulator
  SGGB_RS01955 (SGGB_0345) - 352075..353238 (+) 1164 WP_012961420.1 glycosyltransferase family 4 protein -
  SGGB_RS01960 (SGGB_0346) sufC 353352..354122 (+) 771 WP_003063299.1 Fe-S cluster assembly ATPase SufC -
  SGGB_RS01965 (SGGB_0347) sufD 354196..355458 (+) 1263 WP_012961421.1 Fe-S cluster assembly protein SufD -
  SGGB_RS01970 (SGGB_0348) - 355460..356692 (+) 1233 WP_009853400.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28762.55 Da        Isoelectric Point: 4.0664

>NTDB_id=48897 SGGB_RS01950 WP_009853397.1 351318..352073(+) (mecA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTEAHEKLGKIEEMMEGAVEEVLTEQAQAEPTEEDINPSDYVHYV
LDFPTLEAVVAFAKAIDFPVEASELYKDGGLYHMTILLDLQNHPSYYANLMYARLLEYASAGTKTRAYLQEHGVEMLADD
AVAKLKMIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=48897 SGGB_RS01950 WP_009853397.1 351318..352073(+) (mecA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGTGGCATGGAGTT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTACTCAGTAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGTGGAATGCTTAGCTTTCGTGTGACACCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAAATC
AATAAAGAAATTAATTTCGAAGATTTAGCTGCATTCGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGCTTTCTAAAGGTGATACTGAGGCGCATGAAAAATTAGGAAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAGGAAGTTCTCACAGAACAAGCTCAAGCAGAGCCAACAGAAGAGGATATTAATCCATCTGATTATGTTCATTATGTC
CTTGATTTTCCAACACTTGAAGCTGTCGTAGCTTTTGCTAAAGCAATTGATTTTCCAGTTGAAGCATCAGAACTCTACAA
AGATGGCGGTCTTTACCACATGACCATTTTACTTGATTTGCAAAATCATCCGTCTTACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCGCAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTGTTGAAATGTTAGCAGATGAC
GCTGTTGCAAAATTAAAAATGATTGAGTTGGTATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RH68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.742

98.805

0.669
  mecA Streptococcus thermophilus LMD-9

60.729

98.406

0.598
  mecA Streptococcus thermophilus LMG 18311

60.324

98.406

0.594
  mecA Streptococcus pneumoniae Rx1

48.617

100

0.49
  mecA Streptococcus pneumoniae D39

48.617

100

0.49
  mecA Streptococcus pneumoniae R6

48.617

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.617

100

0.49

Multiple sequence alignment