Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KFU89_RS02170 Genome accession   NZ_CP073943
Coordinates   446265..447389 (+) Length   374 a.a.
NCBI ID   WP_257156253.1    Uniprot ID   -
Organism   Escherichia coli strain MB52     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 441265..452389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU89_RS02145 (KFU89_02110) mscL 441391..441801 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  KFU89_RS02150 (KFU89_02115) trkA 441931..443307 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  KFU89_RS02155 (KFU89_02120) rsmB 443329..444618 (-) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KFU89_RS02160 (KFU89_02125) fmt 444664..445611 (-) 948 WP_000004473.1 methionyl-tRNA formyltransferase -
  KFU89_RS02165 (KFU89_02130) def 445626..446135 (-) 510 WP_000114984.1 peptide deformylase -
  KFU89_RS02170 (KFU89_02135) dprA 446265..447389 (+) 1125 WP_257156253.1 DNA-protecting protein DprA Machinery gene
  KFU89_RS02175 (KFU89_02140) smg 447361..447834 (+) 474 WP_000460680.1 DUF494 family protein Smg -
  KFU89_RS02180 (KFU89_02145) yrdD 447863..448405 (+) 543 WP_001129722.1 type I DNA topoisomerase -
  KFU89_RS02185 (KFU89_02150) tsaC 448410..448982 (+) 573 WP_001301412.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  KFU89_RS02190 (KFU89_02155) aroE 448987..449805 (+) 819 WP_000451243.1 shikimate dehydrogenase -
  KFU89_RS02195 (KFU89_02160) yrdB 449802..450059 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  KFU89_RS02200 (KFU89_02165) yrdA 450035..450589 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40944.88 Da        Isoelectric Point: 6.3122

>NTDB_id=488496 KFU89_RS02170 WP_257156253.1 446265..447389(+) (dprA) [Escherichia coli strain MB52]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGSIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=488496 KFU89_RS02170 WP_257156253.1 446265..447389(+) (dprA) [Escherichia coli strain MB52]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTTCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.677

82.888

0.412
  dprA Vibrio cholerae strain A1552

49.677

82.888

0.412
  dprA Haemophilus influenzae Rd KW20

45.104

90.107

0.406
  dprA Glaesserella parasuis strain SC1401

45.104

90.107

0.406
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393