Detailed information NTG0488170

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF739_RS10575
• Genome accession: NZ_CP062346
• Coordinates: 2158342..2159229 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_261
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2153342..2164229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF739_RS10545 (IF739_10440)	-	2154044..2154835 (+)	792	WP_240017916.1	alpha/beta hydrolase family protein	-
IF739_RS10550 (IF739_10445)	-	2155080..2155535 (+)	456	WP_047213013.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF739_RS14335	-	2155657..2155758 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF739_RS10560 (IF739_10455)	-	2155818..2157242 (-)	1425	WP_047213011.1	alkaline phosphatase	-
IF739_RS10565 (IF739_10460)	-	2157440..2157640 (+)	201	WP_000604725.1	hypothetical protein	-
IF739_RS10570 (IF739_10465)	braR	2157666..2158331 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF739_RS10575 (IF739_10470)	braS	2158342..2159229 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF739_RS10580 (IF739_10475)	-	2159337..2160092 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
IF739_RS10585 (IF739_10480)	-	2160089..2162089 (+)	2001	WP_240017919.1	ABC transporter permease	-
IF739_RS10590 (IF739_10485)	-	2162754..2162867 (+)	114	WP_072357681.1	hypothetical protein	-
IF739_RS10595 (IF739_10490)	-	2163249..2163509 (+)	261	WP_014532715.1	hypothetical protein	-
IF739_RS10600 (IF739_10495)	-	2163519..2164016 (+)	498	WP_001065267.1	glutathione peroxidase	-
IF739_RS10605 (IF739_10500)	-	2164124..2164216 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=488170 IF739_RS10575 WP_000143420.1 2158342..2159229(+) (braS) [Staphylococcus aureus strain NAS_AN_261]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=488170 IF739_RS10575 WP_000143420.1 2158342..2159229(+) (braS) [Staphylococcus aureus strain NAS_AN_261]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993