Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KDN44_RS02145 Genome accession   NZ_CP073360
Coordinates   445140..446264 (+) Length   374 a.a.
NCBI ID   WP_000228538.1    Uniprot ID   -
Organism   Escherichia coli strain EC11     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 440140..451264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KDN44_RS02120 mscL 440266..440676 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  KDN44_RS02125 trkA 440806..442182 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  KDN44_RS02130 rsmB 442204..443493 (-) 1290 WP_088167554.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KDN44_RS02135 fmt 443539..444486 (-) 948 WP_000004451.1 methionyl-tRNA formyltransferase -
  KDN44_RS02140 def 444501..445010 (-) 510 WP_000114984.1 peptide deformylase -
  KDN44_RS02145 dprA 445140..446264 (+) 1125 WP_000228538.1 DNA-protecting protein DprA Machinery gene
  KDN44_RS02150 smg 446236..446709 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  KDN44_RS02155 yrdD 446738..447280 (+) 543 WP_001129719.1 type I DNA topoisomerase -
  KDN44_RS02160 tsaC 447285..447857 (+) 573 WP_001365949.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  KDN44_RS02165 aroE 447862..448680 (+) 819 WP_000451211.1 shikimate dehydrogenase -
  KDN44_RS02170 yrdB 448677..448934 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  KDN44_RS02175 yrdA 448910..449464 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40955.86 Da        Isoelectric Point: 6.3122

>NTDB_id=487242 KDN44_RS02145 WP_000228538.1 445140..446264(+) (dprA) [Escherichia coli strain EC11]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=487242 KDN44_RS02145 WP_000228538.1 445140..446264(+) (dprA) [Escherichia coli strain EC11]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

45.135

98.93

0.447
  dprA Vibrio cholerae strain A1552

45.135

98.93

0.447
  dprA Haemophilus influenzae Rd KW20

45.401

90.107

0.409
  dprA Glaesserella parasuis strain SC1401

45.133

90.642

0.409
  dprA Legionella pneumophila strain ERS1305867

44.848

88.235

0.396