Detailed information NTG0486014

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: IGB12_RS03020
• Genome accession: NZ_CP062068
• Coordinates: 640778..642937 (+)
• Length: 719 a.a.
• NCBI ID: WP_014567253.1
• Uniprot ID: -
• Organism: Lactobacillus johnsonii strain GHZ10a
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 635778..647937

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGB12_RS02995 (IGB12_02995)	udk	636366..637001 (-)	636	WP_004895448.1	uridine kinase	-
IGB12_RS03000 (IGB12_03000)	-	637330..637482 (+)	153	WP_004896917.1	hypothetical protein	-
IGB12_RS03005 (IGB12_03005)	-	637773..638822 (+)	1050	WP_069168405.1	IS30 family transposase	-
IGB12_RS03010 (IGB12_03010)	-	638884..639960 (+)	1077	WP_244966825.1	GHKL domain-containing protein	-
IGB12_RS03015 (IGB12_03015)	-	639968..640765 (+)	798	WP_192006358.1	LytTR family DNA-binding domain-containing protein	-
IGB12_RS03020 (IGB12_03020)	comA	640778..642937 (+)	2160	WP_014567253.1	peptide cleavage/export ABC transporter	Regulator
IGB12_RS03025 (IGB12_03025)	-	642948..643541 (+)	594	WP_192006360.1	HlyD family efflux transporter periplasmic adaptor subunit	-
IGB12_RS03030 (IGB12_03030)	-	643691..643885 (+)	195	WP_011161718.1	hypothetical protein	-
IGB12_RS03035 (IGB12_03035)	-	643998..644288 (+)	291	WP_011161719.1	bacteriocin immunity protein	-
IGB12_RS03040 (IGB12_03040)	-	644373..645605 (+)	1233	WP_023599386.1	CPBP family intramembrane glutamic endopeptidase	-
IGB12_RS03045 (IGB12_03045)	-	645701..645976 (+)	276	WP_014567255.1	hypothetical protein	-
IGB12_RS03050 (IGB12_03050)	-	646181..646411 (+)	231	WP_004896932.1	hypothetical protein	-
IGB12_RS03055 (IGB12_03055)	-	646534..646848 (+)	315	WP_004896933.1	bacteriocin immunity protein	-
IGB12_RS03060 (IGB12_03060)	-	646851..647135 (+)	285	WP_004896934.1	hypothetical protein	-

Sequence

Protein

• Length: 719 a.a.
• Molecular weight: 81082.30 Da
• Isoelectric Point: 7.0026

>NTDB_id=486014 IGB12_RS03020 WP_014567253.1 640778..642937(+) (comA) [Lactobacillus johnsonii strain GHZ10a]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDS
IQYPFIVHVLKQGELLHYYVVLKNTKHYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGIVLAAQNMTLFGITLLALPVYA
VVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKAESLQTALKTFIQ
LSLNVIILWVGARVVIQGQMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LEGMIEYKHVHYRYGYGTDVLKNINLKIKPDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRPDISEEDVIKACQIAGIDQEIASLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDQGQIVEEGSHEELMEQHGFYYDLVKG

Nucleotide

• Length: 2160 bp

>NTDB_id=486014 IGB12_RS03020 WP_014567253.1 640778..642937(+) (comA) [Lactobacillus johnsonii strain GHZ10a]
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAAATGGATTGCGGAGTTGCTTGTCTAGCAATGATTTT
AAAGCAGTATCATTCTCGTGTATCTTTAGCACATTTGCGTCATGAAGCTCGCACAAATCTTGAAGGTACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATAGT
ATTCAATACCCTTTTATTGTGCATGTTCTTAAGCAAGGAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGCA
TTACTTAGTAATTGCCGACCCAGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGAATAGTGTTAGCTGCTCAAAATATGACTTTATTTGGAATCACATTATTAGCTTTACCAGTATATGCT
GTAGTAATTCTGGGATTTACTAAGAAATTTGAAAAGTTAAATGATGAACAAATGGAGAGCAATGCAGTACTAAGTTCTTC
AGTCATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGTAGAATCGATAGCC
AATTTGTAAATTATTTAAAGAAGTCATTTAAATATAGTAAGGCTGAGAGTTTGCAGACGGCGTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGCGCACGAGTAGTGATACAAGGACAGATGAGTATCGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGTCTTCAATCAGCTAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAGGAATGATTGAATACAAGCATGTTCATTATCGATATGGTTATGGGACGGATGTTTTAAAAAATATTAATCTAAA
AATTAAGCCAGATGAAAAATTAGCAATTGTTGGCATGAGTGGATCAGGAAAATCGACAATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCATAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTATTACTCGGCTGCAGACCGGATAT
TAGCGAAGAAGATGTAATTAAAGCCTGTCAGATTGCTGGAATTGATCAGGAGATAGCTAGTTTGCCACTACAATTCGAGA
CAAAGTTAGATGAGAATGCCAAGATTTTATCCGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTCTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGCTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCGGAACGTGCGGATAAAGTAGTTGTAATTGATC
AGGGGCAAATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-439)

• ABC transporter (ABC_tran) (501-651)

• Peptidase C39 family (Peptidase_C39) (7-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	56.601	99.026	0.56
comA	Streptococcus mitis SK321	56.32	99.026	0.558
comA	Streptococcus pneumoniae Rx1	56.32	99.026	0.558
comA	Streptococcus pneumoniae D39	56.32	99.026	0.558
comA	Streptococcus pneumoniae R6	56.32	99.026	0.558
comA	Streptococcus pneumoniae TIGR4	56.18	99.026	0.556
comA	Streptococcus gordonii str. Challis substr. CH1	55.337	99.026	0.548
comA/nlmT	Streptococcus mutans UA159	53.041	98.331	0.522