Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   NMBH4476_RS10820 Genome accession   NC_017516
Coordinates   2099627..2100076 (-) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria meningitidis H44/76     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2089576..2100463 2099627..2100076 within 0


Gene organization within MGE regions


Location: 2089576..2100463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBH4476_RS10775 (NMBH4476_1945) - 2089576..2091219 (+) 1644 WP_002223143.1 DUF4435 domain-containing protein -
  NMBH4476_RS10780 (NMBH4476_1946) - 2091263..2091445 (+) 183 WP_002223144.1 hypothetical protein -
  NMBH4476_RS10785 (NMBH4476_1947) lpt3 2091657..2093234 (+) 1578 WP_002223145.1 lipooligosaccharide phosphoethanolamine transferase -
  NMBH4476_RS15755 - 2093336..2094562 (+) 1227 Protein_2014 DUF3418 domain-containing protein -
  NMBH4476_RS10790 (NMBH4476_1948) - 2094935..2096719 (+) 1785 Protein_2015 DUF3418 domain-containing protein -
  NMBH4476_RS10795 (NMBH4476_1949) - 2096752..2097843 (-) 1092 WP_002225876.1 XRE family transcriptional regulator -
  NMBH4476_RS10800 (NMBH4476_1950) - 2097859..2098503 (-) 645 WP_002223148.1 hypothetical protein -
  NMBH4476_RS15230 (NMBH4476_1952) - 2098860..2099012 (+) 153 WP_002223150.1 hypothetical protein -
  NMBH4476_RS15940 (NMBH4476_1953) - 2099269..2099537 (+) 269 Protein_2019 5'-nucleotidase -
  NMBH4476_RS10820 (NMBH4476_1954) comP 2099627..2100076 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=48073 NMBH4476_RS10820 WP_002214937.1 2099627..2100076(-) (comP) [Neisseria meningitidis H44/76]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=48073 NMBH4476_RS10820 WP_002214937.1 2099627..2100076(-) (comP) [Neisseria meningitidis H44/76]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGGTTTAAACAAACATCTACCAAGTGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49

Multiple sequence alignment