Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   IBL27_RS08700 Genome accession   NZ_CP061071
Coordinates   1791758..1792480 (-) Length   240 a.a.
NCBI ID   WP_002273406.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1786758..1797480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS08675 (IBL27_08675) sufU 1786793..1787227 (-) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -
  IBL27_RS08680 (IBL27_08680) - 1787214..1788443 (-) 1230 WP_002288881.1 cysteine desulfurase -
  IBL27_RS08685 (IBL27_08685) sufD 1788448..1789710 (-) 1263 WP_002308720.1 Fe-S cluster assembly protein SufD -
  IBL27_RS08690 (IBL27_08690) sufC 1789748..1790518 (-) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  IBL27_RS08695 (IBL27_08695) rgpG 1790592..1791752 (-) 1161 WP_002262748.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  IBL27_RS08700 (IBL27_08700) mecA 1791758..1792480 (-) 723 WP_002273406.1 adaptor protein MecA Regulator
  IBL27_RS08705 (IBL27_08705) - 1792570..1793415 (-) 846 WP_002262750.1 undecaprenyl-diphosphate phosphatase -
  IBL27_RS08710 (IBL27_08710) - 1793473..1795374 (-) 1902 WP_002308723.1 DUF2207 domain-containing protein -
  IBL27_RS08715 (IBL27_08715) - 1795526..1797079 (+) 1554 WP_002266996.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28029.61 Da        Isoelectric Point: 4.2116

>NTDB_id=480273 IBL27_RS08700 WP_002273406.1 1791758..1792480(-) (mecA) [Streptococcus mutans B04Sm5]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKGETKEKRDYVHFVLDFPDIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=480273 IBL27_RS08700 WP_002273406.1 1791758..1792480(-) (mecA) [Streptococcus mutans B04Sm5]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGGACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCTCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTGATATTCAACAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCCGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

99.167

100

0.992
  mecA Streptococcus thermophilus LMD-9

58.197

100

0.592
  mecA Streptococcus thermophilus LMG 18311

57.787

100

0.588
  mecA Streptococcus pneumoniae Rx1

48.571

100

0.496
  mecA Streptococcus pneumoniae D39

48.571

100

0.496
  mecA Streptococcus pneumoniae R6

48.571

100

0.496
  mecA Streptococcus pneumoniae TIGR4

48.571

100

0.496