Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   IBL27_RS00220 Genome accession   NZ_CP061071
Coordinates   30977..31543 (+) Length   188 a.a.
NCBI ID   WP_002289046.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 12500..46894 30977..31543 within 0


Gene organization within MGE regions


Location: 12500..46894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS00065 (IBL27_00065) ftsH 12500..14470 (+) 1971 WP_002266494.1 ATP-dependent zinc metalloprotease FtsH -
  IBL27_RS00070 (IBL27_00070) - 14958..16373 (+) 1416 WP_002275393.1 amino acid permease -
  IBL27_RS00180 (IBL27_00180) mreC 23460..24278 (+) 819 WP_002263142.1 rod shape-determining protein MreC -
  IBL27_RS00185 (IBL27_00185) mreD 24280..24786 (+) 507 WP_002263141.1 rod shape-determining protein MreD -
  IBL27_RS00190 (IBL27_00190) gbpB 24896..26191 (+) 1296 WP_002289034.1 glucan-binding protein GbpB -
  IBL27_RS00195 (IBL27_00195) - 26316..27284 (+) 969 WP_002263139.1 ribose-phosphate diphosphokinase -
  IBL27_RS00200 (IBL27_00200) - 27373..28548 (+) 1176 WP_002309165.1 pyridoxal phosphate-dependent aminotransferase -
  IBL27_RS00205 (IBL27_00205) recO 28538..29293 (+) 756 WP_002269787.1 DNA repair protein RecO -
  IBL27_RS00210 (IBL27_00210) plsX 29501..30499 (+) 999 WP_002269788.1 phosphate acyltransferase PlsX -
  IBL27_RS00215 (IBL27_00215) - 30501..30749 (+) 249 WP_002263135.1 acyl carrier protein -
  IBL27_RS00220 (IBL27_00220) comA 30977..31543 (+) 567 WP_002289046.1 ATP-binding cassette domain-containing protein Regulator
  IBL27_RS00225 (IBL27_00225) purC 31679..32386 (+) 708 WP_002263133.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  IBL27_RS00230 (IBL27_00230) - 32396..36121 (+) 3726 WP_002309164.1 phosphoribosylformylglycinamidine synthase -
  IBL27_RS00235 (IBL27_00235) - 36143..36763 (+) 621 WP_002289056.1 DNA alkylation repair protein -
  IBL27_RS00240 (IBL27_00240) purF 36789..38228 (+) 1440 WP_002263130.1 amidophosphoribosyltransferase -
  IBL27_RS00245 (IBL27_00245) purM 38287..39309 (+) 1023 WP_002289058.1 phosphoribosylformylglycinamidine cyclo-ligase -
  IBL27_RS00250 (IBL27_00250) purN 39309..39854 (+) 546 WP_002271558.1 phosphoribosylglycinamide formyltransferase -
  IBL27_RS00255 (IBL27_00255) - 39900..40799 (+) 900 WP_002264110.1 exonuclease domain-containing protein -
  IBL27_RS00260 (IBL27_00260) purH 41135..42685 (+) 1551 WP_002309161.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
  IBL27_RS00265 (IBL27_00265) - 42868..43410 (-) 543 WP_002289062.1 TetR/AcrR family transcriptional regulator -
  IBL27_RS00270 (IBL27_00270) - 43578..44087 (+) 510 WP_002289064.1 HXXEE domain-containing protein -
  IBL27_RS09825 - 44260..44430 (+) 171 Protein_33 type II toxin-antitoxin system RelE family toxin -
  IBL27_RS00275 (IBL27_00275) - 44582..45439 (+) 858 WP_002283085.1 Abi family protein -
  IBL27_RS00280 (IBL27_00280) - 45515..46894 (+) 1380 WP_002283797.1 Eco57I restriction-modification methylase domain-containing protein -

Sequence

Protein


Download         Length: 188 a.a.        Molecular weight: 20785.57 Da        Isoelectric Point: 4.7600

>NTDB_id=480209 IBL27_RS00220 WP_002289046.1 30977..31543(+) (comA) [Streptococcus mutans B04Sm5]
MGKSGSGKTTLAKILAGYYTVSSGDSFLDGEKINYSQLRQLVTYVPQQSYVFTGTILDNLLLGAEEEVTDDRLMEVCSIA
EILDDIKAMPLGFQTQISEDGGLSGGQKQRLAIARALLTRQPVLIFDEATSGLDRDTEEKVIANLSKLDRTIIFIAHRGS
VSYYADRIVEIDSGEKIKDRINHRPFSF

Nucleotide


Download         Length: 567 bp        

>NTDB_id=480209 IBL27_RS00220 WP_002289046.1 30977..31543(+) (comA) [Streptococcus mutans B04Sm5]
ATGGGGAAAAGTGGTTCTGGAAAGACAACTTTGGCAAAAATTCTTGCAGGTTATTATACTGTTAGTAGCGGTGACTCTTT
CTTAGATGGAGAAAAGATAAATTATTCCCAGCTGCGCCAATTAGTAACTTATGTGCCACAGCAGTCTTATGTTTTTACAG
GAACAATCTTAGATAATCTGCTTCTTGGTGCTGAAGAGGAAGTAACGGATGATCGCTTAATGGAAGTTTGTTCAATTGCT
GAAATTTTAGACGATATCAAGGCAATGCCTTTAGGTTTTCAAACACAGATTTCAGAAGACGGCGGTTTATCTGGTGGTCA
AAAACAGCGTTTAGCTATTGCACGTGCTCTCTTAACCAGACAGCCTGTGTTGATTTTTGATGAGGCAACTAGTGGTTTAG
ATCGTGATACCGAAGAAAAAGTTATTGCCAATTTATCTAAATTGGATCGCACGATTATTTTTATTGCTCACCGAGGCAGT
GTTTCTTATTATGCTGATCGAATTGTTGAGATTGACTCTGGAGAGAAAATTAAGGATAGAATAAATCATCGTCCTTTCTC
ATTTTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

51.872

99.468

0.516
  comA Streptococcus gordonii str. Challis substr. CH1

52.198

96.809

0.505
  comA/nlmT Streptococcus mutans UA159

49.468

100

0.495
  comA Streptococcus pneumoniae Rx1

50.273

97.34

0.489
  comA Streptococcus pneumoniae D39

50.273

97.34

0.489
  comA Streptococcus pneumoniae R6

50.273

97.34

0.489
  comA Streptococcus mitis SK321

49.18

97.34

0.479
  comA Streptococcus pneumoniae TIGR4

49.18

97.34

0.479