Detailed information NTG0047977

Bioinformatically predicted

Overview

• Name: dsbA2
• Type: Machinery gene
• Locus tag: NMBM01240149_RS10115
• Genome accession: NC_017514
• Coordinates: 1963361..1964056 (-)
• Length: 231 a.a.
• NCBI ID: WP_002248140.1
• Uniprot ID: A1KVZ3
• Organism: Neisseria meningitidis M01-240149
• Function: DNA binding and uptake; interact with PilQ (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1962319..1963284	1963361..1964056	flank	77

Gene organization within MGE regions

Location: 1962319..1964056

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBM01240149_RS10110 (NMBM01240149_1790)	-	1962319..1963284 (+)	966	WP_014580882.1	IS30-like element IS1655 family transposase	-
NMBM01240149_RS10115 (NMBM01240149_1791)	dsbA2	1963361..1964056 (-)	696	WP_002248140.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 25378.89 Da
• Isoelectric Point: 5.3625

>NTDB_id=47977 NMBM01240149_RS10115 WP_002248140.1 1963361..1964056(-) (dsbA2) [Neisseria meningitidis M01-240149]
MKLKTLALTSLTLLALAACSKQAETSVPADSVQSSSSAPAAPAPLTEGVNYTVLSTPIPQQQAGKVEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEASESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide

• Length: 696 bp

>NTDB_id=47977 NMBM01240149_RS10115 WP_002248140.1 1963361..1964056(-) (dsbA2) [Neisseria meningitidis M01-240149]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGCGT
TCCGGCAGACAGCGTCCAAAGCAGCTCATCTGCTCCGGCAGCCCCAGCCCCATTGACCGAAGGCGTGAACTACACTGTAT
TGTCCACGCCTATCCCGCAACAGCAGGCCGGCAAAGTCGAAGTCTTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTTCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATCGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCCGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

• Thioredoxin (Thioredoxin_4) (64-212)

3D structure

• AlphaFold DB: A1KVZ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dsbA2	Neisseria meningitidis MC58	97.835	100	0.978
dsbA1	Neisseria meningitidis MC58	70.815	100	0.714