Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   NMBM01240149_RS10205 Genome accession   NC_017514
Coordinates   1986651..1987349 (-) Length   232 a.a.
NCBI ID   WP_002223343.1    Uniprot ID   A0A422SVD5
Organism   Neisseria meningitidis M01-240149     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1981651..1992349
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM01240149_RS10190 (NMBM01240149_1805) - 1981964..1983010 (-) 1047 WP_014581246.1 peptidylprolyl isomerase -
  NMBM01240149_RS10195 (NMBM01240149_1806) - 1983112..1985520 (-) 2409 WP_025460893.1 LPS-assembly protein LptD -
  NMBM01240149_RS10200 (NMBM01240149_1807) amgK 1985590..1986594 (+) 1005 WP_014581248.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  NMBM01240149_RS10205 (NMBM01240149_1808) dsbA1 1986651..1987349 (-) 699 WP_002223343.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  NMBM01240149_RS10210 - 1987376..1987567 (+) 192 WP_002233473.1 hypothetical protein -
  NMBM01240149_RS10215 (NMBM01240149_1809) murJ 1987567..1989105 (+) 1539 WP_002248946.1 murein biosynthesis integral membrane protein MurJ -
  NMBM01240149_RS10220 (NMBM01240149_1810) - 1989238..1990194 (+) 957 WP_002248937.1 YheT family hydrolase -
  NMBM01240149_RS10225 (NMBM01240149_1811) trpC 1990244..1991026 (+) 783 WP_002248942.1 indole-3-glycerol phosphate synthase TrpC -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25251.84 Da        Isoelectric Point: 5.1392

>NTDB_id=47978 NMBM01240149_RS10205 WP_002223343.1 1986651..1987349(-) (dsbA1) [Neisseria meningitidis M01-240149]
MKSRQLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLPLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAQ

Nucleotide


Download         Length: 699 bp        

>NTDB_id=47978 NMBM01240149_RS10205 WP_002223343.1 1986651..1987349(-) (dsbA1) [Neisseria meningitidis M01-240149]
ATGAAATCCAGACAACTCGCCCTCGGCGTTGCCGCCCTGTTCGCCCTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACCGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTGAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAGCATGTCGTTTGGCAAAA
AGAAATGCTGCCGCTGGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAGAGCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCCTACGAGTCCCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGTAAATATAAAGTTGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCAGTAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A422SVD5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

98.707

100

0.987
  dsbA2 Neisseria meningitidis MC58

76.72

81.466

0.625

Multiple sequence alignment