Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   H9L18_RS12710 Genome accession   NZ_CP060720
Coordinates   2617339..2618619 (+) Length   426 a.a.
NCBI ID   WP_312844795.1    Uniprot ID   -
Organism   Vagococcus carniphilus strain ATCC BAA-640     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2612339..2623619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9L18_RS12685 (H9L18_12685) - 2612787..2613659 (-) 873 WP_126792610.1 hypothetical protein -
  H9L18_RS12690 (H9L18_12690) - 2613623..2614756 (-) 1134 WP_126792613.1 ThiF family adenylyltransferase -
  H9L18_RS12695 (H9L18_12695) - 2615137..2615925 (+) 789 WP_246433289.1 CPBP family intramembrane glutamic endopeptidase -
  H9L18_RS12700 (H9L18_12700) - 2616165..2616401 (-) 237 Protein_2442 adenylate kinase -
  H9L18_RS12705 (H9L18_12705) rlmH 2616448..2616927 (-) 480 WP_126792617.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  H9L18_RS12710 (H9L18_12710) htrA 2617339..2618619 (+) 1281 WP_312844795.1 trypsin-like peptidase domain-containing protein Regulator
  H9L18_RS12715 (H9L18_12715) - 2618675..2619478 (-) 804 WP_126792621.1 MBL fold metallo-hydrolase -
  H9L18_RS12720 (H9L18_12720) - 2619535..2620365 (-) 831 WP_126792623.1 two-component system regulatory protein YycI -
  H9L18_RS12725 (H9L18_12725) yycH 2620369..2621658 (-) 1290 WP_126792625.1 YycH family regulatory protein -
  H9L18_RS12730 (H9L18_12730) walK 2621655..2623481 (-) 1827 WP_126792627.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 426 a.a.        Molecular weight: 45170.61 Da        Isoelectric Point: 5.0960

>NTDB_id=478053 H9L18_RS12710 WP_312844795.1 2617339..2618619(+) (htrA) [Vagococcus carniphilus strain ATCC BAA-640]
MKRFGVSLLAGALGGMLVVGGYTAINHNSNSSDKVTSVTPSKSEVNDTGKTKVQNAKVDVSTDVTKAVKNVEDAVVSVTT
LQKQQSQLSDLERIFGPSDNNKNDGELAEASEGSGVIYRKDGNKAYIVTNNHVVANADAVSILFNNGEKTEAKIVGTDVY
SDLAVLEISSKNVTTVAEFADSNDIKVGEPALAMGSPLGSTFSNSVSQGIVSAKDRMINNQTEDGQLISSNAIQTDAAIN
PGNSGGALINSSGQVIGINSSKIAQAASGVSAEGMGFAIPSNDVVSIINQLEKGKPVARPMLGVSMIDLNIVSAEERESV
LKLKDKDITNGVVVGGVEKDSPAEKAGIKKYDVITELDGKAINNKSELQSVLYRKKIGDDMDITFYHEGKKQTKKVKLDQ
DSAKLLEKQQKQQKEKESLDQSNFQQ

Nucleotide


Download         Length: 1281 bp        

>NTDB_id=478053 H9L18_RS12710 WP_312844795.1 2617339..2618619(+) (htrA) [Vagococcus carniphilus strain ATCC BAA-640]
ATGAAACGTTTTGGTGTTTCTTTATTAGCTGGTGCTCTAGGTGGCATGCTAGTTGTTGGTGGCTATACTGCTATTAATCA
TAACAGCAATAGTAGCGACAAAGTAACTTCTGTCACTCCTTCAAAAAGTGAAGTTAACGATACAGGTAAAACAAAAGTTC
AAAATGCAAAAGTAGATGTTTCAACTGATGTTACAAAAGCTGTTAAAAATGTAGAGGATGCAGTTGTTTCTGTTACTACT
CTTCAAAAACAACAAAGTCAGCTATCTGATTTAGAACGTATTTTTGGTCCTTCTGACAATAATAAAAATGATGGTGAATT
AGCTGAAGCTAGTGAAGGTAGTGGTGTTATTTACCGAAAAGATGGTAATAAAGCCTACATCGTTACAAACAATCACGTTG
TCGCAAATGCTGACGCTGTAAGTATTCTATTTAATAACGGTGAAAAAACAGAAGCCAAAATTGTTGGAACTGACGTTTAT
AGTGACTTAGCTGTCTTAGAAATTTCATCTAAAAATGTAACAACTGTGGCCGAATTTGCTGACTCTAATGATATCAAAGT
TGGTGAGCCTGCATTAGCTATGGGATCTCCATTAGGTTCTACCTTCTCTAATTCAGTTTCTCAAGGTATCGTTTCTGCGA
AAGACCGTATGATTAATAACCAAACTGAAGATGGTCAATTAATTAGTAGTAACGCGATTCAAACGGATGCTGCCATTAAC
CCTGGTAACTCTGGTGGTGCTCTAATTAATTCAAGTGGACAAGTCATCGGTATTAACTCAAGCAAAATAGCTCAAGCAGC
TTCTGGTGTGTCTGCTGAAGGTATGGGATTTGCTATTCCAAGTAACGATGTTGTTTCTATTATTAACCAACTTGAAAAAG
GTAAACCTGTTGCTCGTCCAATGCTTGGTGTGTCAATGATTGACCTAAACATTGTTAGTGCTGAAGAACGTGAAAGTGTT
CTTAAATTAAAAGATAAAGATATCACTAACGGTGTAGTTGTTGGTGGTGTAGAAAAAGATTCACCTGCAGAAAAAGCTGG
TATTAAAAAATATGATGTCATTACAGAATTAGATGGTAAAGCCATCAATAATAAATCAGAATTACAATCTGTTTTATATC
GCAAAAAAATCGGTGATGACATGGATATAACTTTCTATCACGAAGGTAAAAAACAAACTAAAAAAGTTAAACTTGACCAA
GATTCAGCTAAATTGCTAGAAAAACAACAAAAACAACAAAAAGAAAAAGAAAGTTTAGACCAAAGTAATTTCCAACAATA
A

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(203-402)

Trypsin-like peptidase domain (Trypsin_2)

(113-258)

PDZ domain (PDZ_2)

(300-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.256

87.089

0.481
  htrA Streptococcus gordonii str. Challis substr. CH1

46.04

94.836

0.437
  htrA Streptococcus mitis NCTC 12261

50.877

80.282

0.408
  htrA Streptococcus pneumoniae TIGR4

50

80.282

0.401
  htrA Streptococcus pneumoniae D39

50

80.282

0.401
  htrA Streptococcus pneumoniae Rx1

50

80.282

0.401
  htrA Streptococcus pneumoniae R6

50

80.282

0.401