Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   H7790_RS09335 Genome accession   NZ_CP060645
Coordinates   1900525..1901748 (+) Length   407 a.a.
NCBI ID   WP_136073827.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1349     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1895525..1906748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7790_RS09320 (H7790_09325) - 1898665..1899439 (-) 775 Protein_1806 IS30 family transposase -
  H7790_RS09330 (H7790_09335) rlmH 1899834..1900313 (-) 480 WP_002981964.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  H7790_RS09335 (H7790_09340) htrA 1900525..1901748 (+) 1224 WP_136073827.1 S1C family serine protease Regulator
  H7790_RS09340 (H7790_09345) spo0J 1901837..1902613 (+) 777 WP_032460604.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42776.38 Da        Isoelectric Point: 7.3920

>NTDB_id=477334 H7790_RS09335 WP_136073827.1 1900525..1901748(+) (htrA) [Streptococcus pyogenes strain TSPY1349]
MPSMKHILKSLSILLVGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDTELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=477334 H7790_RS09335 WP_136073827.1 1900525..1901748(+) (htrA) [Streptococcus pyogenes strain TSPY1349]
ATGCCAAGTATGAAACATATCTTAAAATCCTTAAGTATTTTACTAGTTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTCAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACTAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATACTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGACGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(301-396)

Trypsin-like peptidase domain (Trypsin_2)

(109-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.881

99.263

0.614
  htrA Streptococcus gordonii str. Challis substr. CH1

55.473

98.771

0.548
  htrA Streptococcus mitis NCTC 12261

52.927

100

0.533
  htrA Streptococcus pneumoniae Rx1

52.683

100

0.531
  htrA Streptococcus pneumoniae D39

52.683

100

0.531
  htrA Streptococcus pneumoniae R6

52.683

100

0.531
  htrA Streptococcus pneumoniae TIGR4

52.683

100

0.531