Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H7792_RS00650 Genome accession   NZ_CP060643
Coordinates   102438..103466 (+) Length   342 a.a.
NCBI ID   WP_228650395.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY416     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97438..108466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS00640 (H7792_00650) - 101106..101471 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7792_RS00645 (H7792_00655) comYA 101564..102502 (+) 939 WP_111684478.1 competence type IV pilus ATPase ComGA Machinery gene
  H7792_RS00650 (H7792_00660) comYB 102438..103466 (+) 1029 WP_228650395.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7792_RS00655 (H7792_00665) comYC 103468..103794 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  H7792_RS00660 (H7792_00670) comGD 103769..104197 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  H7792_RS00665 (H7792_00675) comGE 104154..104438 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  H7792_RS00670 (H7792_00680) comYF 104431..104865 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7792_RS00675 (H7792_00685) comGG 104849..105175 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  H7792_RS00680 (H7792_00690) comYH 105273..106226 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  H7792_RS00685 (H7792_00695) - 106285..107481 (+) 1197 WP_010921803.1 acetate kinase -
  H7792_RS00690 (H7792_00700) - 107668..107976 (+) 309 Protein_90 hypothetical protein -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 39434.86 Da        Isoelectric Point: 9.6102

>NTDB_id=477178 H7792_RS00650 WP_228650395.1 102438..103466(+) (comYB) [Streptococcus pyogenes strain TSPY416]
MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFVEVIAFLKRSQLLQLDYVLKMEESLLKGQGLADMLSGL
GFSDAILTQISLADRHGNIETTLVAIQHYLNQMARRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHF
PAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIEKSSL
MKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLVVA
VTIVMIYAAILLPIYQNMGGIF

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=477178 H7792_RS00650 WP_228650395.1 102438..103466(+) (comYB) [Streptococcus pyogenes strain TSPY416]
TTGATCAGCTTTTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAGTAAACATCAGCATAA
ATTCATTCAATTACTAGCTAATCTTTTATCTACAGGATTTAGCTTCGTAGAGGTTATTGCTTTTTTAAAAAGAAGCCAGT
TGCTTCAGCTAGATTATGTTCTTAAAATGGAAGAGTCTTTATTAAAAGGACAAGGCTTAGCAGATATGTTGTCGGGTTTA
GGTTTTTCAGATGCTATTCTTACTCAAATTAGTTTAGCTGATAGACACGGTAATATTGAAACAACATTAGTAGCGATTCA
ACATTACTTGAACCAAATGGCAAGGAGAAAAACTGTTGAAGTTATCACCTATCCTCTTATTCTTTTACTTTTTCTTTTTG
TGATGATGCTAGGGTTGAGACGCTATTTAGTCCCTCAATTAGAAACTCAAAATCAGATAACTTACTTTCTTAACCATTTT
CCTGCCTTCTTTATAGGTTTTTGCTCAGGTCTTATTTTGTTGTTCGGGATGGTATGGCTACGATGGCGATCTCAAAGCCG
CTTGAAACTCTATAGTCGGCTAAGCCGTTATCCTTTTTTAGGTAAACTGTTAAAACAATACTTAACTAGTTATTATGCTA
GAGAATGGGGTACGTTAATAGGTCAAGGTCTTGATTTGATGACTATTTTAGACATTATGGCCATTGAGAAATCCTCACTA
ATGAAAGAATTAGCTGAGGACATCAGAATGAGTCTGCTTGAAGGGCAAGCCTTTCACATTAAAGTAGCTACCTACCCTTT
TTTTAAAAAAGAATTAAGTTTAATGATTGAATACGGTGAAATCAAATCGAAACTGGGGGCTGAGTTGGAAATCTATGCCC
AGGAAAGCTGGGAACAATTTTTTAGTCAGCTTTATCAAGTGACACAACTTATTCAACCAGCTATTTTTTTAGTAGTTGCT
GTGACAATCGTCATGATTTATGCGGCAATCCTATTACCAATTTACCAAAATATGGGAGGTATTTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(213-333)

Type II secretion system (T2SS), protein F (T2SSF)

(28-145)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.982

99.123

0.535
  comYB Streptococcus mutans UA159

53.982

99.123

0.535
  comYB Streptococcus gordonii str. Challis substr. CH1

50.294

99.415

0.5
  comGB/cglB Streptococcus mitis NCTC 12261

47.917

98.246

0.471
  comGB/cglB Streptococcus mitis SK321

48.048

97.368

0.468
  comGB/cglB Streptococcus pneumoniae Rx1

45.946

97.368

0.447
  comGB/cglB Streptococcus pneumoniae D39

45.946

97.368

0.447
  comGB/cglB Streptococcus pneumoniae R6

45.946

97.368

0.447
  comGB/cglB Streptococcus pneumoniae TIGR4

45.946

97.368

0.447
  comGB Lactococcus lactis subsp. cremoris KW2

43.077

95.029

0.409