Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   LLH_RS03430 Genome accession   NC_017492
Coordinates   668867..670201 (+) Length   444 a.a.
NCBI ID   WP_080561977.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris A76     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 670206..672732 668867..670201 flank 5


Gene organization within MGE regions


Location: 668867..672732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLH_RS03430 (llh_3535) comEC 668867..670201 (+) 1335 WP_080561977.1 ComEC/Rec2 family competence protein Machinery gene
  LLH_RS03435 (llh_3540) - 670206..671096 (-) 891 WP_014572207.1 IS982-like element IS982B family transposase -
  LLH_RS03440 (llh_3545) comEC 671289..671765 (+) 477 WP_014572208.1 MBL fold metallo-hydrolase Machinery gene
  LLH_RS03445 (llh_3550) - 671842..672732 (+) 891 WP_014572209.1 IS982-like element ISLll1 family transposase -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 51656.64 Da        Isoelectric Point: 9.2839

>NTDB_id=47685 LLH_RS03430 WP_080561977.1 668867..670201(+) (comEC) [Lactococcus cremoris subsp. cremoris A76]
MRFLLIKFPLIFLTYLVVLLYFCIFTYNLPLLILFICSILLALFRKYYLMIPILIVFAVFFLLINSLSIRDNENQPKNLS
KIELIPDTIQVNGDLLSFQGRMNGQKYQVYDTLKSLKEKGFYQNLSQNCQLSFTGNLEIPETQRNFNGFDDQKYLTSQNI
YRQITIQQITNVEIKKNFDLHTLRRKAIVWTQNHFPKPMSDYMTGLLFGFLSKDFNQMSDIYSSLGIIHLFALSGMQVNF
FIDWFRKILLRMGLTRERVNLVQIPFSIFYAFMTGLSVSVLRALFQKNIRLTSLDNIAVTTLVLMLISPKFLLTTGGQLT
LFYAFVISMLNHPFSNLNGLKKVLTESSVLSLCVLPLLIFDFHIFQPLSILLTIIFGFLFDFMLLPLLLCCFLISFLGFS
LNLNYIFQILEWLVYKVDLPLHYPFVLGKPSSLELIILFVYPNC

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=47685 LLH_RS03430 WP_080561977.1 668867..670201(+) (comEC) [Lactococcus cremoris subsp. cremoris A76]
ATGAGATTTCTATTGATTAAATTTCCCCTGATTTTTCTAACTTATCTTGTTGTGCTACTTTATTTTTGTATCTTTACTTA
CAATTTACCCTTGCTTATTTTATTTATTTGCTCAATTTTACTAGCTTTATTCAGAAAATATTATCTAATGATTCCGATAT
TAATTGTTTTTGCTGTATTTTTTCTGTTAATCAATAGTCTTAGTATTAGGGATAATGAAAATCAACCAAAAAATCTCTCA
AAAATTGAATTAATTCCAGATACAATCCAAGTCAATGGTGATTTATTGAGTTTTCAGGGGAGAATGAATGGACAAAAATA
TCAAGTCTATGACACATTGAAAAGTCTAAAAGAGAAAGGGTTTTATCAGAACTTAAGTCAAAATTGTCAGTTAAGTTTCA
CAGGAAACCTTGAAATACCAGAAACTCAGCGAAATTTTAATGGTTTTGATGACCAAAAATATTTAACTAGTCAAAATATC
TATCGACAGATTACCATCCAACAAATTACAAATGTGGAAATAAAAAAGAATTTTGACCTTCATACTTTAAGGCGAAAGGC
AATTGTTTGGACACAAAATCATTTTCCAAAACCGATGAGTGACTATATGACAGGTTTGCTTTTTGGCTTTTTAAGTAAGG
ATTTTAATCAGATGAGCGATATTTACAGCTCTTTAGGAATTATTCATCTTTTTGCTCTATCAGGAATGCAAGTAAATTTT
TTTATTGATTGGTTTCGTAAAATACTTCTTCGCATGGGACTGACGAGAGAAAGAGTGAATCTTGTTCAAATTCCATTTTC
TATTTTTTATGCTTTTATGACGGGATTATCGGTTTCAGTTTTAAGAGCCCTTTTTCAAAAAAATATTCGTCTGACTTCTT
TGGATAATATCGCAGTTACGACATTAGTTTTGATGCTCATAAGTCCAAAATTTTTACTGACAACTGGTGGTCAGCTTACC
TTGTTTTATGCTTTTGTCATTTCGATGCTTAATCATCCTTTTTCTAATTTAAATGGATTGAAAAAAGTGCTGACAGAATC
ATCAGTCCTTTCACTTTGTGTTCTTCCGTTACTCATCTTTGATTTCCATATTTTTCAGCCTCTTTCAATATTATTAACAA
TTATATTTGGTTTTCTTTTTGATTTTATGTTGCTCCCGCTGCTTTTATGCTGTTTTCTTATATCATTTTTGGGATTTTCG
CTCAATTTAAATTATATTTTTCAAATTCTAGAATGGCTAGTTTATAAAGTTGATTTACCCTTACATTACCCCTTTGTTTT
GGGGAAACCTAGTTCACTCGAATTAATTATTCTATTTGTGTACCCGAATTGCTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(206-440)

Domain of unknown function (DUF4131) (DUF4131)

(27-171)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Lactococcus lactis subsp. cremoris KW2

97.5

99.099

0.966
  comEC/celB Streptococcus mitis SK321

44.368

97.973

0.435
  comEC/celB Streptococcus mitis NCTC 12261

43.678

97.973

0.428
  comEC/celB Streptococcus pneumoniae TIGR4

43.678

97.973

0.428
  comEC/celB Streptococcus pneumoniae Rx1

42.989

97.973

0.421
  comEC/celB Streptococcus pneumoniae D39

42.989

97.973

0.421
  comEC/celB Streptococcus pneumoniae R6

42.989

97.973

0.421

Multiple sequence alignment