NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	J0O73_RS21705	Genome accession	NZ_CP071375
Coordinates	4492030..4493154 (-)	Length	374 a.a.
NCBI ID	WP_153645673.1	Uniprot ID	-
Organism	Escherichia coli strain E105
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4487030..4498154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0O73_RS21675 (J0O73_21655)	yrdA	4488830..4489384 (+)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
J0O73_RS21680 (J0O73_21660)	yrdB	4489360..4489617 (-)	258	WP_001070563.1	DUF1488 domain-containing protein	-
J0O73_RS21685 (J0O73_21665)	aroE	4489614..4490432 (-)	819	WP_053884591.1	shikimate dehydrogenase	-
J0O73_RS21690 (J0O73_21670)	tsaC	4490437..4491009 (-)	573	WP_089637748.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
J0O73_RS21695 (J0O73_21675)	yrdD	4491014..4491556 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
J0O73_RS21700 (J0O73_21680)	smg	4491585..4492058 (-)	474	WP_000460680.1	DUF494 family protein Smg	-
J0O73_RS21705 (J0O73_21685)	dprA	4492030..4493154 (-)	1125	WP_153645673.1	DNA-protecting protein DprA	Machinery gene
J0O73_RS21710 (J0O73_21690)	def	4493284..4493793 (+)	510	WP_000114984.1	peptide deformylase	-
J0O73_RS21715 (J0O73_21695)	fmt	4493808..4494755 (+)	948	WP_089637747.1	methionyl-tRNA formyltransferase	-
J0O73_RS21720 (J0O73_21700)	rsmB	4494801..4496090 (+)	1290	WP_053884587.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
J0O73_RS21725 (J0O73_21705)	trkA	4496112..4497488 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
J0O73_RS21730 (J0O73_21710)	mscL	4497618..4498028 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40923.82 Da Isoelectric Point: 6.1828

                                >NTDB_id=476795 J0O73_RS21705 WP_153645673.1 4492030..4493154(-) (dprA) [Escherichia coli strain E105]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFGETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGLHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=476795 J0O73_RS21705 WP_153645673.1 4492030..4493154(-) (dprA) [Escherichia coli strain E105]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTGGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT

TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCTTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	44.595	98.93	0.441
dprA	Vibrio cholerae strain A1552	44.595	98.93	0.441
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	43.363	90.642	0.393

Detailed information NTG0476795