Detailed information NTG0476630

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: HUG14_RS01090
• Genome accession: NZ_CP060580
• Coordinates: 231903..234113 (-)
• Length: 736 a.a.
• NCBI ID: WP_187398453.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain K_LL005
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 226903..239113

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUG14_RS01060 (HUG14_01060)	atpA	226946..228448 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
HUG14_RS01065 (HUG14_01065)	-	228635..229162 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
HUG14_RS01070 (HUG14_01070)	atpF	229164..229670 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
HUG14_RS01075 (HUG14_01075)	atpB	229685..230398 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
HUG14_RS01080 (HUG14_01080)	-	230443..230658 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
HUG14_RS01085 (HUG14_01085)	-	230843..231619 (-)	777	WP_058206315.1	alpha/beta hydrolase family protein	-
HUG14_RS01090 (HUG14_01090)	comEC	231903..234113 (-)	2211	WP_187398453.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HUG14_RS01095 (HUG14_01095)	comEA	234094..234741 (-)	648	WP_033899944.1	ComEA family DNA-binding protein	Machinery gene
HUG14_RS01100 (HUG14_01100)	-	234801..236162 (-)	1362	WP_029344292.1	ABC transporter permease	-
HUG14_RS01105 (HUG14_01105)	-	236159..237091 (-)	933	WP_187398454.1	ABC transporter ATP-binding protein	-
HUG14_RS01110 (HUG14_01110)	-	237196..237594 (-)	399	WP_004255236.1	hypothetical protein	-
HUG14_RS01115 (HUG14_01115)	-	237698..238261 (-)	564	WP_129881050.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84508.13 Da
• Isoelectric Point: 9.6913

>NTDB_id=476630 HUG14_RS01090 WP_187398453.1 231903..234113(-) (comEC) [Lactococcus lactis strain K_LL005]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYSFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNSDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=476630 HUG14_RS01090 WP_187398453.1 231903..234113(-) (comEC) [Lactococcus lactis strain K_LL005]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATTCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGCACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACTCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (206-446)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.902	100	0.769
comEC/celB	Streptococcus mitis SK321	44.474	100	0.448
comEC/celB	Streptococcus mitis NCTC 12261	44.34	100	0.447
comEC/celB	Streptococcus pneumoniae TIGR4	43.338	100	0.438
comEC/celB	Streptococcus pneumoniae Rx1	42.934	100	0.433
comEC/celB	Streptococcus pneumoniae D39	42.934	100	0.433
comEC/celB	Streptococcus pneumoniae R6	42.934	100	0.433