NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	J0G23_RS11975	Genome accession	NZ_CP071263
Coordinates	2435596..2436720 (-)	Length	374 a.a.
NCBI ID	WP_000228540.1	Uniprot ID	-
Organism	Escherichia coli strain MEI003
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2430596..2441720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J0G23_RS11945 (J0G23_11870)	yrdA	2432396..2432950 (+)	555	WP_001286217.1	gamma carbonic anhydrase family protein	-
J0G23_RS11950 (J0G23_11875)	yrdB	2432926..2433183 (-)	258	WP_001070562.1	DUF1488 domain-containing protein	-
J0G23_RS11955 (J0G23_11880)	aroE	2433180..2433998 (-)	819	WP_000451230.1	shikimate dehydrogenase	-
J0G23_RS11960 (J0G23_11885)	tsaC	2434003..2434575 (-)	573	WP_001310090.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
J0G23_RS11965 (J0G23_11890)	yrdD	2434580..2435122 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
J0G23_RS11970 (J0G23_11895)	smg	2435151..2435624 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
J0G23_RS11975 (J0G23_11900)	dprA	2435596..2436720 (-)	1125	WP_000228540.1	DNA-protecting protein DprA	Machinery gene
J0G23_RS11980 (J0G23_11905)	def	2436850..2437359 (+)	510	WP_000114984.1	peptide deformylase	-
J0G23_RS11985 (J0G23_11910)	fmt	2437374..2438321 (+)	948	WP_000004443.1	methionyl-tRNA formyltransferase	-
J0G23_RS11990 (J0G23_11915)	rsmB	2438367..2439656 (+)	1290	WP_001551736.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
J0G23_RS11995 (J0G23_11920)	trkA	2439678..2441054 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
J0G23_RS12000 (J0G23_11925)	mscL	2441184..2441594 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 41035.00 Da Isoelectric Point: 6.1815

                                >NTDB_id=476440 J0G23_RS11975 WP_000228540.1 2435596..2436720(-) (dprA) [Escherichia coli strain MEI003]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSYIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=476440 J0G23_RS11975 WP_000228540.1 2435596..2436720(-) (dprA) [Escherichia coli strain MEI003]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGTATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGACGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	43.62	90.107	0.393
dprA	Legionella pneumophila strain ERS1305867	44.073	87.968	0.388

Detailed information NTG0476440