Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I653_RS19590 Genome accession   NC_020832
Coordinates   3955030..3956232 (-) Length   400 a.a.
NCBI ID   WP_041520081.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis str. BAB-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3950030..3961232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I653_RS19570 (I653_19810) rocE 3950144..3951547 (-) 1404 WP_015483954.1 amino acid permease -
  I653_RS19575 (I653_19815) rocD 3951770..3952975 (-) 1206 WP_015483955.1 ornithine aminotransferase -
  I653_RS19580 (I653_19820) rocR 3953216..3954601 (+) 1386 WP_015385164.1 arginine utilization regulatory protein RocR -
  I653_RS19585 (I653_19825) - 3954583..3954768 (-) 186 Protein_3941 ATP-binding protein -
  I653_RS21180 - 3954884..3955010 (-) 127 Protein_3942 hypothetical protein -
  I653_RS19590 (I653_19830) htrA 3955030..3956232 (-) 1203 WP_041520081.1 serine protease HtrC Regulator
  I653_RS19595 (I653_19835) vicX 3956314..3957108 (-) 795 WP_015483958.1 MBL fold metallo-hydrolase Regulator
  I653_RS19600 (I653_19840) walI 3957130..3957972 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  I653_RS19605 (I653_19845) walH 3957959..3959326 (-) 1368 WP_015483959.1 WalRK two-component regulatory system regulator WalH -
  I653_RS19610 (I653_19850) walK 3959316..3961151 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42799.52 Da        Isoelectric Point: 5.5340

>NTDB_id=47544 I653_RS19590 WP_041520081.1 3955030..3956232(-) (htrA) [Bacillus subtilis subsp. subtilis str. BAB-1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAGERVGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=47544 I653_RS19590 WP_041520081.1 3955030..3956232(-) (htrA) [Bacillus subtilis subsp. subtilis str. BAB-1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTATCTTTCAAATGAAGGGCTGGATACGGGCG
CTTTAGATCAGCAGCAGAACAACAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAATCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGG
TGAAAGGGTTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGACTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(186-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

PDZ domain (PDZ_2)

(295-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.325

99.25

0.43
  htrA Streptococcus gordonii str. Challis substr. CH1

41.045

100

0.413
  htrA Streptococcus mitis NCTC 12261

42.746

96.5

0.412
  htrA Streptococcus pneumoniae TIGR4

44.848

82.5

0.37
  htrA Streptococcus pneumoniae D39

44.848

82.5

0.37
  htrA Streptococcus pneumoniae Rx1

44.848

82.5

0.37
  htrA Streptococcus pneumoniae R6

44.848

82.5

0.37

Multiple sequence alignment