Detailed information NTG0473535

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: H6S61_RS06095
• Genome accession: NZ_CP060047
• Coordinates: 1208319..1209188 (+)
• Length: 289 a.a.
• NCBI ID: WP_038941424.1
• Uniprot ID: B7U4R2
• Organism: Vibrio vulnificus strain 2497-87
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1203319..1214188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H6S61_RS06075 (H6S61_06075)	nadC	1203687..1204574 (+)	888	WP_130354580.1	carboxylating nicotinate-nucleotide diphosphorylase	-
H6S61_RS06080 (H6S61_06080)	pilA	1204797..1205264 (+)	468	WP_130270837.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
H6S61_RS06085 (H6S61_06085)	pilB	1205264..1206952 (+)	1689	WP_103187652.1	type IV-A pilus assembly ATPase PilB	Machinery gene
H6S61_RS06090 (H6S61_06090)	pilC	1207000..1208226 (+)	1227	WP_130247867.1	type II secretion system F family protein	Machinery gene
H6S61_RS06095 (H6S61_06095)	pilD	1208319..1209188 (+)	870	WP_038941424.1	A24 family peptidase	Machinery gene
H6S61_RS06100 (H6S61_06100)	coaE	1209190..1209798 (+)	609	WP_045593985.1	dephospho-CoA kinase	-
H6S61_RS06105 (H6S61_06105)	zapD	1209831..1210571 (+)	741	WP_017421189.1	cell division protein ZapD	-
H6S61_RS06110 (H6S61_06110)	yacG	1210634..1210828 (+)	195	WP_038941426.1	DNA gyrase inhibitor YacG	-
H6S61_RS06115 (H6S61_06115)	rplS	1211060..1211413 (-)	354	WP_011079544.1	50S ribosomal protein L19	-
H6S61_RS06120 (H6S61_06120)	trmD	1211455..1212204 (-)	750	WP_011079543.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
H6S61_RS06125 (H6S61_06125)	rimM	1212232..1212780 (-)	549	WP_038941427.1	ribosome maturation factor RimM	-
H6S61_RS06130 (H6S61_06130)	rpsP	1212796..1213044 (-)	249	WP_011079541.1	30S ribosomal protein S16	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32245.33 Da
• Isoelectric Point: 6.8198

>NTDB_id=473535 H6S61_RS06095 WP_038941424.1 1208319..1209188(+) (pilD) [Vibrio vulnificus strain 2497-87]
MDALQYYPWLYIGLASLFGLLVGSFLNVVIYRLPKIMELEWRQECAESFPEYKISPPTETLTLSTPRSSCPSCHTPIRVR
DNIPVFSWLALRGKCHHCQTKISARYPFVEALSAFLCGLIAWKFGYAPITVALIGFTLVLIAATFIDLDTMLLPDQLTLP
LTWAGIALALLEISPVSLQDSVIGAMAGYLCLWSVYHLFRLLTGKEGMGYGDFKLLAALGAWLGWQYLPMIILLSSVVGL
IFGLIQLRLQKQGIEMAFPFGPYLAIAGWVALMWGDSLMSWYLNYLIGA

Nucleotide

• Length: 870 bp

>NTDB_id=473535 H6S61_RS06095 WP_038941424.1 1208319..1209188(+) (pilD) [Vibrio vulnificus strain 2497-87]
ATGGACGCGTTACAGTACTACCCTTGGCTTTATATTGGTTTAGCTTCCCTGTTTGGCTTACTGGTAGGCAGCTTTCTTAA
CGTCGTCATCTACCGTCTACCAAAAATAATGGAACTGGAGTGGCGCCAAGAGTGTGCAGAGTCCTTTCCTGAATACAAAA
TATCACCGCCGACAGAAACCCTAACATTAAGCACGCCGCGTTCAAGTTGTCCTTCGTGTCATACCCCAATACGAGTTCGA
GATAATATTCCTGTCTTTAGTTGGCTAGCTCTAAGAGGAAAATGTCACCATTGCCAGACGAAAATCAGTGCTCGCTATCC
TTTTGTTGAAGCACTGAGCGCCTTTTTGTGCGGCCTAATCGCTTGGAAGTTCGGCTATGCACCAATTACCGTAGCACTGA
TTGGGTTTACTTTAGTCTTGATCGCCGCCACCTTCATCGACTTAGATACCATGCTACTGCCTGATCAGCTGACACTGCCG
CTGACGTGGGCTGGCATTGCGCTAGCGTTACTTGAGATAAGCCCAGTATCTCTGCAAGATTCAGTGATCGGTGCGATGGC
GGGTTATCTCTGCCTTTGGAGCGTTTATCACCTTTTCCGCTTGCTGACAGGAAAAGAAGGCATGGGTTACGGAGACTTTA
AATTGCTTGCGGCACTTGGAGCTTGGCTCGGCTGGCAATATCTACCGATGATCATCTTACTCTCTTCGGTTGTCGGGTTG
ATCTTTGGTCTCATTCAACTCAGATTGCAAAAACAAGGCATTGAGATGGCTTTTCCATTTGGGCCTTATCTAGCCATTGC
TGGTTGGGTCGCCTTGATGTGGGGAGATAGCTTGATGTCTTGGTATCTCAACTATCTTATAGGGGCATGA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (137-244)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: B7U4R2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	77.855	100	0.779
pilD	Vibrio cholerae strain A1552	71.875	99.654	0.716
pilD	Acinetobacter nosocomialis M2	53.986	95.502	0.516
pilD	Acinetobacter baumannii D1279779	53.986	95.502	0.516
pilD	Neisseria gonorrhoeae MS11	47.636	95.156	0.453