NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	I6K11_RS12055	Genome accession	NZ_CP070134
Coordinates	2284459..2285583 (-)	Length	374 a.a.
NCBI ID	WP_001521436.1	Uniprot ID	-
Organism	Escherichia coli strain FDAARGOS_1281
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2279459..2290583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K11_RS12025 (I6K11_12035)	yrdA	2281259..2281813 (+)	555	WP_001286217.1	gamma carbonic anhydrase family protein	-
I6K11_RS12030 (I6K11_12040)	yrdB	2281789..2282046 (-)	258	WP_001521433.1	DUF1488 domain-containing protein	-
I6K11_RS12035 (I6K11_12045)	aroE	2282043..2282861 (-)	819	WP_001521434.1	shikimate dehydrogenase	-
I6K11_RS12040 (I6K11_12050)	tsaC	2282866..2283438 (-)	573	WP_029701540.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
I6K11_RS12045 (I6K11_12055)	yrdD	2283443..2283985 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
I6K11_RS12050 (I6K11_12060)	smg	2284014..2284487 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
I6K11_RS12055 (I6K11_12065)	dprA	2284459..2285583 (-)	1125	WP_001521436.1	DNA-protecting protein DprA	Machinery gene
I6K11_RS12060 (I6K11_12070)	def	2285713..2286222 (+)	510	WP_000114984.1	peptide deformylase	-
I6K11_RS12065 (I6K11_12075)	fmt	2286237..2287184 (+)	948	WP_000004456.1	methionyl-tRNA formyltransferase	-
I6K11_RS12070 (I6K11_12080)	rsmB	2287230..2288519 (+)	1290	WP_001308993.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
I6K11_RS12075 (I6K11_12085)	trkA	2288541..2289917 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
I6K11_RS12080 (I6K11_12090)	mscL	2290047..2290457 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40994.94 Da Isoelectric Point: 6.2655

                                >NTDB_id=473049 I6K11_RS12055 WP_001521436.1 2284459..2285583(-) (dprA) [Escherichia coli strain FDAARGOS_1281]

MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=473049 I6K11_RS12055 WP_001521436.1 2284459..2285583(-) (dprA) [Escherichia coli strain FDAARGOS_1281]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	43.939	88.235	0.388

Detailed information NTG0473049