NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	I6L00_RS18665	Genome accession	NZ_CP070098
Coordinates	3751451..3752575 (-)	Length	374 a.a.
NCBI ID	WP_001521436.1	Uniprot ID	-
Organism	Escherichia coli strain FDAARGOS_1370
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3746451..3757575

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L00_RS18635 (I6L00_18590)	yrdA	3748251..3748805 (+)	555	WP_001286217.1	gamma carbonic anhydrase family protein	-
I6L00_RS18640 (I6L00_18595)	yrdB	3748781..3749038 (-)	258	WP_001521433.1	DUF1488 domain-containing protein	-
I6L00_RS18645 (I6L00_18600)	aroE	3749035..3749853 (-)	819	WP_001521434.1	shikimate dehydrogenase	-
I6L00_RS18650 (I6L00_18605)	tsaC	3749858..3750430 (-)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
I6L00_RS18655 (I6L00_18610)	yrdD	3750435..3750977 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
I6L00_RS18660 (I6L00_18615)	smg	3751006..3751479 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
I6L00_RS18665 (I6L00_18620)	dprA	3751451..3752575 (-)	1125	WP_001521436.1	DNA-protecting protein DprA	Machinery gene
I6L00_RS18670 (I6L00_18625)	def	3752705..3753214 (+)	510	WP_000114984.1	peptide deformylase	-
I6L00_RS18675 (I6L00_18630)	fmt	3753229..3754176 (+)	948	WP_000004456.1	methionyl-tRNA formyltransferase	-
I6L00_RS18680 (I6L00_18635)	rsmB	3754222..3755511 (+)	1290	WP_001308993.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
I6L00_RS18685 (I6L00_18640)	trkA	3755533..3756909 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
I6L00_RS18690 (I6L00_18645)	mscL	3757039..3757449 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40994.94 Da Isoelectric Point: 6.2655

                                >NTDB_id=472638 I6L00_RS18665 WP_001521436.1 3751451..3752575(-) (dprA) [Escherichia coli strain FDAARGOS_1370]

MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=472638 I6L00_RS18665 WP_001521436.1 3751451..3752575(-) (dprA) [Escherichia coli strain FDAARGOS_1370]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	43.939	88.235	0.388

Detailed information NTG0472638