Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   R2866_RS01410 Genome accession   NC_017451
Coordinates   272812..274032 (+) Length   406 a.a.
NCBI ID   WP_005666687.1    Uniprot ID   -
Organism   Haemophilus influenzae R2866     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 267812..279032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2866_RS01390 (R2866_0278) corC 268778..269677 (-) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -
  R2866_RS01395 (R2866_0279) ampD 270309..270860 (-) 552 WP_005666680.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  R2866_RS01400 (R2866_0280) pilA 270975..271424 (+) 450 WP_005666683.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  R2866_RS01405 (R2866_0281) pilB 271421..272815 (+) 1395 WP_005666685.1 GspE/PulE family protein Machinery gene
  R2866_RS01410 (R2866_0282) pilC 272812..274032 (+) 1221 WP_005666687.1 type II secretion system F family protein Machinery gene
  R2866_RS01415 (R2866_0283) pilD 274029..274721 (+) 693 WP_005666688.1 prepilin peptidase Machinery gene
  R2866_RS01420 (R2866_0284) rho 274776..276038 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  R2866_RS01425 (R2866_0285) metJ 276285..276602 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  R2866_RS01430 (R2866_0286) cueR 276616..277002 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  R2866_RS01435 (R2866_0287) - 277079..277285 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  R2866_RS01440 (R2866_0288) - 277360..277566 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  R2866_RS01445 (R2866_0289) - 277641..277847 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46207.43 Da        Isoelectric Point: 9.8218

>NTDB_id=47259 R2866_RS01410 WP_005666687.1 272812..274032(+) (pilC) [Haemophilus influenzae R2866]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMVYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQQKNQLISVTPIFGTIQKLSRLVNFSRSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=47259 R2866_RS01410 WP_005666687.1 272812..274032(+) (pilC) [Haemophilus influenzae R2866]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCGCACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGGTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGTTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCGCAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTTTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.966
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment