NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	I6K16_RS09320	Genome accession	NZ_CP069893
Coordinates	1931309..1932433 (-)	Length	374 a.a.
NCBI ID	WP_000228527.1	Uniprot ID	-
Organism	Escherichia coli strain FDAARGOS_1286
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1926309..1937433

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K16_RS09290 (I6K16_09290)	yrdA	1928109..1928663 (+)	555	WP_204669833.1	gamma carbonic anhydrase family protein	-
I6K16_RS09295 (I6K16_09295)	yrdB	1928639..1928896 (-)	258	WP_001070566.1	DUF1488 domain-containing protein	-
I6K16_RS09300 (I6K16_09300)	aroE	1928893..1929711 (-)	819	WP_000451227.1	shikimate dehydrogenase	-
I6K16_RS09305 (I6K16_09305)	tsaC	1929716..1930288 (-)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
I6K16_RS09310 (I6K16_09310)	yrdD	1930293..1930835 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
I6K16_RS09315 (I6K16_09315)	smg	1930864..1931337 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
I6K16_RS09320 (I6K16_09320)	dprA	1931309..1932433 (-)	1125	WP_000228527.1	DNA-protecting protein DprA	Machinery gene
I6K16_RS09325 (I6K16_09325)	def	1932563..1933072 (+)	510	WP_000114986.1	peptide deformylase	-
I6K16_RS09330 (I6K16_09330)	fmt	1933087..1934034 (+)	948	WP_000004420.1	methionyl-tRNA formyltransferase	-
I6K16_RS09335 (I6K16_09335)	rsmB	1934080..1935369 (+)	1290	WP_001318069.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
I6K16_RS09340 (I6K16_09340)	trkA	1935391..1936767 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
I6K16_RS09345 (I6K16_09345)	mscL	1936897..1937307 (+)	411	WP_000022444.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40982.87 Da Isoelectric Point: 6.2662

                                >NTDB_id=471090 I6K16_RS09320 WP_000228527.1 1931309..1932433(-) (dprA) [Escherichia coli strain FDAARGOS_1286]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLSDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=471090 I6K16_RS09320 WP_000228527.1 1931309..1932433(-) (dprA) [Escherichia coli strain FDAARGOS_1286]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGTGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCTCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGTCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.032	82.888	0.406
dprA	Vibrio cholerae strain A1552	49.032	82.888	0.406
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Legionella pneumophila strain ERS1305867	43.658	90.642	0.396
dprA	Haemophilus influenzae Rd KW20	43.917	90.107	0.396

Detailed information NTG0471090