Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   I6K87_RS05515 Genome accession   NZ_CP069892
Coordinates   1123807..1125681 (-) Length   624 a.a.
NCBI ID   WP_049533517.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1118807..1130681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS05485 (I6K87_05485) - 1118963..1119280 (+) 318 WP_049516901.1 DUF960 domain-containing protein -
  I6K87_RS05490 (I6K87_05490) - 1119409..1119780 (-) 372 WP_049533513.1 S1 RNA-binding domain-containing protein -
  I6K87_RS05495 (I6K87_05495) - 1119782..1121182 (-) 1401 WP_195995634.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6K87_RS05500 (I6K87_05500) vraR 1121222..1121854 (-) 633 WP_003028406.1 response regulator transcription factor Regulator
  I6K87_RS05505 (I6K87_05505) - 1121856..1122851 (-) 996 WP_195995636.1 sensor histidine kinase -
  I6K87_RS05510 (I6K87_05510) liaF 1122848..1123546 (-) 699 WP_003028409.1 cell wall-active antibiotics response protein LiaF -
  I6K87_RS05515 (I6K87_05515) stkP 1123807..1125681 (-) 1875 WP_049533517.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6K87_RS05520 (I6K87_05520) - 1125678..1126418 (-) 741 WP_049533518.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6K87_RS05525 (I6K87_05525) rsmB 1126436..1127749 (-) 1314 WP_049533519.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6K87_RS05530 (I6K87_05530) fmt 1127739..1128674 (-) 936 WP_049533520.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67702.78 Da        Isoelectric Point: 9.3373

>NTDB_id=470997 I6K87_RS05515 WP_049533517.1 1123807..1125681(-) (stkP) [Streptococcus anginosus strain FDAARGOS_1357]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSATKSTPAPTKEVVS
STPTPTPKAKKKRRLRTRYKVLLSAVVLVIVALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSVK
KDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKIEEVESSEYAAGTVVDQTP
AAGSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQTPEAGQS
LNLKSDRIVLYVYEPKTEDSSTSESSSQSNSSSDKTSPSSSSSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=470997 I6K87_RS05515 WP_049533517.1 1123807..1125681(-) (stkP) [Streptococcus anginosus strain FDAARGOS_1357]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAGAATCATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTTGCGGTTAAGGTTCTAAGAACCAATTACCAGACAGATCCGATTG
CTGTAGCACGTTTTCAAAGAGAGGCGCGAGCCATGGCAGATTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGCCAGCAATATCTAGCAATGGAGTATGTGGCTGGACTTGACTTGAAACGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTGCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCGCATACGCATGGGATTGTTC
ACCGTGATTTAAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACTGACTTTGGAATTGCAGTAGCT
TTTGCAGAAACGAGCTTAACGCAAACCAACTCTATGTTGGGGTCTGTACATTATTTGTCACCAGAACAGGCGCGTGGTTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGTCACATTCCTTATGATG
GGGATAGTGCTGTGACGATTGCCCTACAGCATTTCCAAAAGCCCCTACCGTCCATTATTGCTGAAAACCCAAATGTTCCA
CAAGCATTGGAAAATGTAGTCATCAAGGCAACGGCAAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGTTTATCTGCTGACCGTCGAAATGAGAAAAAGCTAGTTTTTGATGACACTGCTAAAGCAGACACAA
AGACACTGCCGAAAGTATCACAAAATACCTTGACTTCTGCGACGAAGTCAACACCTGCTCCTACAAAAGAAGTAGTCAGT
AGTACGCCTACGCCTACGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGCTATAAAGTTTTGTTATCAGCGGTGGT
TTTAGTCATCGTAGCTCTGGTGGCTTTAGTCTATTTGAGTCCGTCAAATGTAAAAATCCCAGATGTTACTGGAAAAACTA
TTGCCCAAGCACGTTCTGCAATCGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTTAAA
AAAGATTCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTCAAA
AGGGACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCTATCAACAATCTGGTACAAAAATACA
AGGTTTCAAAAGGCTTGATTAAAATAGAAGAAGTTGAAAGTAGTGAGTATGCGGCAGGAACAGTTGTTGATCAAACACCA
GCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCACGAT
GCCAAGCTATATCGGCTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATATTG
AAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAACCCCAGAAGCTGGTCAGTCT
TTGAATTTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAACCGAAGATTCTTCAACATCTGAAAGTAGTTC
ACAATCTAATAGCAGCTCAGATAAAACTAGCCCATCCTCTAGTAGTTCGTCAACTAGTGGTAATGATGGAAGCAGCTCAA
AAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterProScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(364-427)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(433-500)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.154

93.75

0.62
  stkP Streptococcus pneumoniae D39

65.812

93.75

0.617
  stkP Streptococcus pneumoniae R6

65.812

93.75

0.617
  stkP Streptococcus pneumoniae Rx1

65.641

93.75

0.615
  pknB Streptococcus mutans UA159

58.974

93.75

0.553
  stkP/pknB Streptococcus salivarius strain HSISS4

55.833

96.154

0.537