Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   H1R75_RS05375 Genome accession   NZ_CP059471
Coordinates   1037040..1038365 (-) Length   441 a.a.
NCBI ID   WP_024344056.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1032040..1043365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS05350 (H1R75_05350) - 1032594..1033649 (-) 1056 WP_080651031.1 BMP family lipoprotein -
  H1R75_RS05355 (H1R75_05355) deoC 1033838..1034503 (-) 666 WP_074483529.1 deoxyribose-phosphate aldolase -
  H1R75_RS05360 (H1R75_05360) - 1035006..1035596 (-) 591 WP_024344058.1 class I SAM-dependent methyltransferase -
  H1R75_RS05365 (H1R75_05365) coaA 1035710..1036630 (+) 921 WP_033152659.1 type I pantothenate kinase -
  H1R75_RS05370 (H1R75_05370) rpsT 1036706..1036957 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  H1R75_RS05375 (H1R75_05375) ciaH 1037040..1038365 (-) 1326 WP_024344056.1 sensor histidine kinase Regulator
  H1R75_RS05380 (H1R75_05380) ciaR 1038355..1039029 (-) 675 WP_024344055.1 response regulator transcription factor Regulator
  H1R75_RS05385 (H1R75_05385) - 1039183..1041726 (-) 2544 WP_182001140.1 M1 family metallopeptidase -
  H1R75_RS05390 (H1R75_05390) phoU 1041935..1042588 (-) 654 WP_024344053.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50148.05 Da        Isoelectric Point: 7.5433

>NTDB_id=469827 H1R75_RS05375 WP_024344056.1 1037040..1038365(-) (ciaH) [Streptococcus equinus strain MDC1]
MLNNIQKKLSTGTFSHFFHFFAVFTGIFVIMTIIILQIMRYGLYSSVDTTLQNAANNASDYVTRTMERSDSIQSDNTINE
SGKNKSSSNDGLSNVSVLLYDCNGKIVNALDAFIQFGSLTTSVNDDKIGEISEEKMTTIFGQTEKYHVLTVRVYSSDYPT
IQYATFLISVRQLDEANERYVTITITVMVIFWIISILASVYLANWTRKPILESYEKQKRFVENASHELRTPLAVLQNRLE
SLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIHPSTFNEIFENYQMIAHENNKKFTAHNLA
NRPIKSDKTLLKQLMTILFDNAIKYTGDDGVIEFTIKTTERQTILTIADNGPGVSDADKQKIFDRFYRVDKARTRQQGGF
GLGLSLAKQIVDALKGDIQVKDNKPKGTIFEVRFNRHNFGK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=469827 H1R75_RS05375 WP_024344056.1 1037040..1038365(-) (ciaH) [Streptococcus equinus strain MDC1]
ATGCTGAATAATATACAGAAAAAATTATCAACGGGGACTTTCTCACACTTTTTCCATTTTTTTGCTGTGTTTACAGGGAT
TTTCGTTATTATGACAATTATTATCCTGCAAATCATGCGATATGGTTTATATTCTTCTGTCGACACGACGTTACAAAATG
CTGCAAATAATGCCAGTGATTACGTTACGAGAACGATGGAGAGAAGTGATTCGATTCAATCTGATAATACGATTAATGAG
TCAGGAAAAAATAAATCGAGTTCAAATGATGGATTGAGTAATGTTAGTGTCCTTTTGTATGATTGCAACGGTAAAATAGT
TAATGCTTTAGATGCCTTTATTCAATTTGGCTCACTAACGACGAGTGTTAATGATGATAAAATCGGTGAAATAAGCGAAG
AGAAGATGACTACGATTTTCGGTCAAACTGAAAAGTATCACGTCTTGACTGTCAGAGTTTATAGTAGTGATTATCCAACA
ATTCAATACGCAACCTTTCTAATTAGTGTTCGTCAGCTTGACGAGGCAAATGAAAGATATGTGACAATTACTATTACAGT
TATGGTTATCTTTTGGATTATTTCAATTTTAGCGAGTGTTTATCTTGCAAACTGGACTCGTAAACCGATTCTTGAAAGTT
ATGAGAAACAGAAACGCTTTGTTGAGAATGCCAGTCATGAGTTGAGAACGCCGCTTGCTGTTTTGCAAAATCGTCTTGAA
AGTTTGTTTAGACGTCCAGATGCAACAATTTTAGATAATAGCGAAAGTATTGCTGCAAGTCTTGATGAAGTGCGAAATAT
GCGTATTCTGACAACAAATCTTTTAAATCTTGCTAGACGTGATGATGGTTTGAAAGTTGAATTGGAAGAGATTCATCCAT
CAACCTTTAACGAGATTTTTGAAAATTATCAGATGATTGCTCACGAAAATAATAAAAAGTTTACTGCACACAATTTAGCT
AATCGTCCGATAAAATCAGATAAGACTCTTTTGAAACAACTAATGACTATTTTATTTGATAATGCCATTAAGTACACTGG
TGATGATGGCGTTATTGAATTTACCATTAAAACAACAGAACGCCAAACTATTTTAACTATTGCTGATAACGGACCTGGTG
TTAGTGATGCCGATAAGCAGAAGATTTTTGATCGCTTTTACCGTGTCGACAAGGCAAGGACACGTCAACAAGGTGGATTT
GGTTTGGGTTTGTCTCTAGCGAAGCAAATTGTTGATGCTTTGAAGGGTGATATTCAGGTTAAAGATAACAAACCAAAAGG
AACTATTTTTGAAGTTCGTTTCAACAGACATAATTTTGGTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(217-283)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.447

98.413

0.585
  ciaH Streptococcus pneumoniae Rx1

51.835

98.866

0.512
  ciaH Streptococcus pneumoniae D39

51.835

98.866

0.512
  ciaH Streptococcus pneumoniae R6

51.835

98.866

0.512
  ciaH Streptococcus pneumoniae TIGR4

51.835

98.866

0.512