Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   H1R75_RS02145 Genome accession   NZ_CP059471
Coordinates   382380..383141 (+) Length   253 a.a.
NCBI ID   WP_182001577.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 377380..388141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS02130 (H1R75_02130) - 377786..379357 (-) 1572 WP_021141661.1 ABC transporter permease subunit -
  H1R75_RS02135 (H1R75_02135) - 379494..381386 (+) 1893 WP_182001576.1 DUF2207 domain-containing protein -
  H1R75_RS02140 (H1R75_02140) - 381438..382277 (+) 840 WP_003067592.1 undecaprenyl-diphosphate phosphatase -
  H1R75_RS02145 (H1R75_02145) mecA 382380..383141 (+) 762 WP_182001577.1 adaptor protein MecA Regulator
  H1R75_RS02150 (H1R75_02150) - 383143..384306 (+) 1164 WP_182001578.1 glycosyltransferase family 4 protein -
  H1R75_RS02155 (H1R75_02155) sufC 384428..385198 (+) 771 WP_021141665.1 Fe-S cluster assembly ATPase SufC -
  H1R75_RS02160 (H1R75_02160) sufD 385276..386538 (+) 1263 WP_074629241.1 Fe-S cluster assembly protein SufD -
  H1R75_RS02165 (H1R75_02165) - 386540..387772 (+) 1233 WP_182001579.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29069.93 Da        Isoelectric Point: 4.0757

>NTDB_id=469809 H1R75_RS02145 WP_182001577.1 382380..383141(+) (mecA) [Streptococcus equinus strain MDC1]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMMAKGDTEAHEKLGKIEEMMEGAVEEVLTEHAKQADTEPEEDVKPSDYVH
YVLDFPSLEATVAFSKAIDFPVEASELYKMDGAYYMTILLDLQNQPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVAKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=469809 H1R75_RS02145 WP_182001577.1 382380..383141(+) (mecA) [Streptococcus equinus strain MDC1]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGAGGAATGGAGTT
AAAAGACTTTTTGATTCCGCAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAGTTAGATTTACCAGATAATT
TCAAAGATAGCGGCATGCTTAGTTTTCGTGTGACACCACGTAAAGACCGTCTTGATGTATTTGTCACAAAATCAGAAATT
AACAAAGATATCAATTTTGAAGATTTAGCTGCATTTGACGATGTGTCTAATATGTCACCAGAAGAATTCTTTAAAACGCT
AGAACAAACGATGATGGCTAAAGGTGACACTGAAGCTCATGAAAAATTAGGTAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAAGAAGTCTTGACAGAGCACGCTAAGCAAGCAGATACAGAACCTGAAGAAGATGTAAAACCATCTGATTATGTTCAT
TACGTCTTAGATTTTCCAAGCTTAGAAGCAACAGTTGCTTTTTCTAAAGCGATTGATTTTCCTGTGGAAGCTTCTGAGCT
TTACAAGATGGATGGCGCTTATTACATGACAATTTTGCTTGATTTGCAGAACCAACCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTACTTGCAAGAACACGCAGTTGAACTATTGACG
GATGATGCCGTTGCAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.4

98.814

0.656
  mecA Streptococcus thermophilus LMD-9

60.643

98.419

0.597
  mecA Streptococcus thermophilus LMG 18311

59.839

98.419

0.589
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494