NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	JSU12_RS02145	Genome accession	NZ_CP069677
Coordinates	445319..446443 (+)	Length	374 a.a.
NCBI ID	WP_000228538.1	Uniprot ID	-
Organism	Escherichia coli O126:H45 strain MIN10
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 440319..451443

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JSU12_RS02120 (JSU12_02120)	mscL	440445..440855 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
JSU12_RS02125 (JSU12_02125)	trkA	440985..442361 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
JSU12_RS02130 (JSU12_02130)	rsmB	442383..443672 (-)	1290	WP_000744779.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
JSU12_RS02135 (JSU12_02135)	fmt	443718..444665 (-)	948	WP_000004451.1	methionyl-tRNA formyltransferase	-
JSU12_RS02140 (JSU12_02140)	def	444680..445189 (-)	510	WP_000114984.1	peptide deformylase	-
JSU12_RS02145 (JSU12_02145)	dprA	445319..446443 (+)	1125	WP_000228538.1	DNA-protecting protein DprA	Machinery gene
JSU12_RS02150 (JSU12_02150)	smg	446415..446888 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
JSU12_RS02155 (JSU12_02155)	yrdD	446917..447459 (+)	543	WP_208207854.1	type I DNA topoisomerase	-
JSU12_RS02160 (JSU12_02160)	tsaC	447464..448036 (+)	573	WP_001365949.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
JSU12_RS02165 (JSU12_02165)	aroE	448041..448859 (+)	819	WP_000451211.1	shikimate dehydrogenase	-
JSU12_RS02170 (JSU12_02170)	yrdB	448856..449113 (+)	258	WP_001070563.1	DUF1488 domain-containing protein	-
JSU12_RS02175 (JSU12_02175)	yrdA	449089..449643 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40955.86 Da Isoelectric Point: 6.3122

                                >NTDB_id=469583 JSU12_RS02145 WP_000228538.1 445319..446443(+) (dprA) [Escherichia coli O126:H45 strain MIN10]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=469583 JSU12_RS02145 WP_000228538.1 445319..446443(+) (dprA) [Escherichia coli O126:H45 strain MIN10]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT

TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	45.135	98.93	0.447
dprA	Vibrio cholerae strain A1552	45.135	98.93	0.447
dprA	Haemophilus influenzae Rd KW20	45.401	90.107	0.409
dprA	Glaesserella parasuis strain SC1401	45.133	90.642	0.409
dprA	Legionella pneumophila strain ERS1305867	44.848	88.235	0.396

Detailed information NTG0469583