Detailed information NTG0046810

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: HPSA_RS00220
• Genome accession: NC_017361
• Coordinates: 39931..41073 (+)
• Length: 380 a.a.
• NCBI ID: WP_001045896.1
• Uniprot ID: E8QTP2
• Organism: Helicobacter pylori SouthAfrica7
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 34931..46073

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPSA_RS00185 (HPSA_00160)	panD	35370..35720 (+)	351	WP_000142294.1	aspartate 1-decarboxylase	-
HPSA_RS00190 (HPSA_00165)	-	35731..36024 (+)	294	WP_000347932.1	YbaB/EbfC family nucleoid-associated protein	-
HPSA_RS00195 (HPSA_00170)	-	36024..37019 (+)	996	WP_000468493.1	PDZ domain-containing protein	-
HPSA_RS00200 (HPSA_00175)	comB6	37025..38089 (+)	1065	WP_014534702.1	P-type conjugative transfer protein TrbL	Machinery gene
HPSA_RS00205 (HPSA_00180)	comB7	38105..38218 (+)	114	WP_001217877.1	hypothetical protein	Machinery gene
HPSA_RS00210 (HPSA_00185)	comB8	38215..38958 (+)	744	WP_000660575.1	type IV secretion system protein	Machinery gene
HPSA_RS00215 (HPSA_00190)	comB9	38958..39938 (+)	981	WP_001213934.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HPSA_RS00220 (HPSA_00195)	comB10	39931..41073 (+)	1143	WP_001045896.1	DNA type IV secretion system protein ComB10	Machinery gene
HPSA_RS00225 (HPSA_00200)	-	41138..42550 (+)	1413	WP_000693966.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
HPSA_RS00230 (HPSA_00205)	gmd	42570..43715 (+)	1146	WP_000659837.1	GDP-mannose 4,6-dehydratase	-
HPSA_RS00235 (HPSA_00210)	-	43708..44640 (+)	933	WP_001002514.1	GDP-L-fucose synthase family protein	-
HPSA_RS08050 (HPSA_00220)	-	45003..45425 (-)	423	WP_000524151.1	hypothetical protein	-

Sequence

Protein

• Length: 380 a.a.
• Molecular weight: 42294.02 Da
• Isoelectric Point: 9.6704

>NTDB_id=46810 HPSA_RS00220 WP_001045896.1 39931..41073(+) (comB10) [Helicobacter pylori SouthAfrica7]
MNKWLKGVLIVAGGFVTITTISLIYHQKPKAPLNNPPSLLNDDEVKYPLQDYTFTPSLQPTSTESSKDATIKALQEQLRV
ALKALNSKEMNLPKEETKELANPPIEPKANTTPPKKDFSLKQLDLLASRITPFKQSPKNYEENLIFPVDNPKGIDGFTNL
KEKDIATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFAHMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIV
WSRIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEEATNFFGDYLLM
QLMRQSGMGINQVVNQILRDKSKIAPIVIIREGSRVFISPNTDIFFPIPKDNEVIAEFLE

Nucleotide

• Length: 1143 bp

>NTDB_id=46810 HPSA_RS00220 WP_001045896.1 39931..41073(+) (comB10) [Helicobacter pylori SouthAfrica7]
ATGAATAAATGGCTTAAGGGGGTGCTGATTGTTGCAGGGGGTTTTGTAACGATTACAACAATTTCTTTAATCTACCACCA
AAAGCCAAAAGCCCCCTTAAACAACCCACCTTCTCTTTTAAATGACGATGAGGTGAAATACCCCTTACAGGACTACACTT
TCACTCCAAGCTTGCAACCAACCTCTACAGAAAGCTCCAAAGACGCCACTATAAAAGCCTTACAAGAACAGCTAAGAGTC
GCTTTAAAAGCCCTAAATTCCAAAGAAATGAATCTTCCTAAAGAAGAAACTAAAGAACTTGCCAACCCTCCCATAGAACC
AAAAGCAAACACAACCCCCCCTAAAAAAGACTTTTCTCTAAAGCAACTAGATTTATTAGCCTCTCGCATCACCCCTTTCA
AACAAAGCCCTAAAAATTACGAAGAAAATTTGATTTTCCCGGTGGATAACCCTAAAGGGATCGATGGCTTTACTAACCTT
AAAGAAAAAGACATCGCCACCAATGAAAACAAGCTTTTACGCACCATTACAGCGGATAAAATGATACCTGCATTTTTGAT
CACGCCTATTTCTAGCCAGATCGCTGGTAAAGTCATCGCGCAAGTGGAGAGCGATATTTTCGCTCACATGGGAAAGGCTG
TTTTAATCCCTAAAGGTTCTAAAGTCATAGGTTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTG
TGGAGTAGGATCATCACCCCCCATGGCATTAATATCATGCTCACTAACGCTAAAGGGGCGGACATTAAAGGTTATAACGG
CTTGGTGGGGGAATTGATTGAAAGGAACTTCCAACGCTATGGCGTGCCACTATTACTTTCTACGCTCACTAACGGCTTAT
TGATTGGGATCACTTCAGCTTTAAACAATAGAGGCAATAAAGAAGAAGCGACTAATTTCTTTGGGGATTATCTTTTAATG
CAATTGATGAGGCAAAGCGGTATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGACAAGAGCAAAATCGCCCCCAT
TGTCATCATTAGAGAGGGGAGCAGGGTATTCATTTCGCCTAATACTGACATTTTCTTCCCTATACCCAAAGACAATGAAG
TCATCGCTGAGTTTTTGGAGTGA

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (175-366)

3D structure

• AlphaFold DB: E8QTP2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	92.368	100	0.924