Detailed information NTG0046806

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: HPSA_RS00200
• Genome accession: NC_017361
• Coordinates: 37025..38089 (+)
• Length: 354 a.a.
• NCBI ID: WP_014534702.1
• Uniprot ID: E8QTN8
• Organism: Helicobacter pylori SouthAfrica7
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 32025..43089

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPSA_RS00170 (HPSA_00145)	-	32468..32881 (+)	414	WP_001023012.1	universal stress protein	-
HPSA_RS00175 (HPSA_00150)	-	32883..33158 (+)	276	WP_000708367.1	ATP-dependent Clp protease adaptor ClpS	-
HPSA_RS00180 (HPSA_00155)	-	33158..35380 (+)	2223	WP_000357230.1	AAA family ATPase	-
HPSA_RS00185 (HPSA_00160)	panD	35370..35720 (+)	351	WP_000142294.1	aspartate 1-decarboxylase	-
HPSA_RS00190 (HPSA_00165)	-	35731..36024 (+)	294	WP_000347932.1	YbaB/EbfC family nucleoid-associated protein	-
HPSA_RS00195 (HPSA_00170)	-	36024..37019 (+)	996	WP_000468493.1	PDZ domain-containing protein	-
HPSA_RS00200 (HPSA_00175)	comB6	37025..38089 (+)	1065	WP_014534702.1	P-type conjugative transfer protein TrbL	Machinery gene
HPSA_RS00205 (HPSA_00180)	comB7	38105..38218 (+)	114	WP_001217877.1	hypothetical protein	Machinery gene
HPSA_RS00210 (HPSA_00185)	comB8	38215..38958 (+)	744	WP_000660575.1	type IV secretion system protein	Machinery gene
HPSA_RS00215 (HPSA_00190)	comB9	38958..39938 (+)	981	WP_001213934.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HPSA_RS00220 (HPSA_00195)	comB10	39931..41073 (+)	1143	WP_001045896.1	DNA type IV secretion system protein ComB10	Machinery gene
HPSA_RS00225 (HPSA_00200)	-	41138..42550 (+)	1413	WP_000693966.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-

Sequence

Protein

• Length: 354 a.a.
• Molecular weight: 40071.97 Da
• Isoelectric Point: 8.5806

>NTDB_id=46806 HPSA_RS00200 WP_014534702.1 37025..38089(+) (comB6) [Helicobacter pylori SouthAfrica7]
MKNDAYEIILSWFITPLTAILGRFAEFFLYTLHAQFVFNSAVALAFMLFAYKSLKEQNFFSASAILEALWFVGFFALFNY
ALKNPSHFYEFFQNAIFILPNMLTHALSQSLNAFSNHTLSLDFIFNHGFYALSFISDLSHNEISVWLFLSVLQALFLSVL
FAIIILVYLEVHVWCSLGALFLAFGFFKTWRSVVFACLKKCLALGFYKPFLLLVGFLNVSVTKALINAHMQEQQDLSLLL
VVALFLCCVFIIGVPFFINALFRVQNSLKETYKLATNLSANLSQSALNSLQYITTPPVTTTPSSAPASTSESVSKEKETH
SPTFKVETTQLDVKIPNFKQKKVKKDTINTKNEI

Nucleotide

• Length: 1065 bp

>NTDB_id=46806 HPSA_RS00200 WP_014534702.1 37025..38089(+) (comB6) [Helicobacter pylori SouthAfrica7]
ATGAAAAATGACGCTTATGAAATCATTCTTTCTTGGTTTATCACGCCTCTCACGGCGATTTTAGGGCGTTTTGCTGAATT
TTTCCTCTACACCTTGCATGCGCAATTCGTGTTCAATAGCGCGGTCGCTTTAGCGTTCATGCTCTTTGCTTATAAAAGTT
TGAAAGAGCAGAATTTCTTTAGCGCTAGCGCGATTTTAGAAGCGTTATGGTTTGTGGGTTTTTTTGCGCTTTTTAACTAC
GCTTTGAAAAACCCTTCGCATTTTTATGAATTTTTTCAAAACGCAATTTTTATTTTACCCAACATGCTCACCCATGCCCT
TTCTCAAAGCTTGAACGCTTTTTCCAACCACACGCTTTCATTAGATTTTATCTTCAATCATGGGTTTTATGCCCTTAGTT
TTATCAGCGATTTGAGCCATAATGAAATATCCGTGTGGCTTTTTTTAAGCGTTTTGCAAGCGCTTTTTTTGAGCGTGCTG
TTTGCGATCATTATTTTAGTGTATTTGGAAGTGCATGTGTGGTGCTCTTTAGGGGCGCTGTTTTTAGCGTTTGGGTTTTT
TAAAACCTGGAGGAGCGTCGTGTTTGCATGCCTTAAAAAATGCCTAGCCCTTGGGTTTTACAAGCCTTTTTTATTACTGG
TTGGGTTTTTGAATGTGTCGGTTACTAAAGCTTTAATCAACGCTCATATGCAAGAACAACAAGATTTGAGCCTTTTATTG
GTGGTAGCGTTATTTTTGTGTTGCGTTTTTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAATAG
CCTTAAAGAAACTTACAAACTCGCTACAAATTTGAGCGCTAACCTCAGCCAAAGCGCTCTTAATTCCTTGCAATACATTA
CTACCCCACCTGTTACTACCACTCCCTCTAGCGCTCCTGCTTCTACAAGCGAAAGCGTCTCTAAAGAAAAGGAAACGCAT
TCCCCCACATTCAAGGTAGAAACTACCCAATTAGATGTAAAAATTCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATAC
AATAAATACAAAAAACGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: E8QTN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	89.831	100	0.898