Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPSA_RS00210 Genome accession   NC_017361
Coordinates   38215..38958 (+) Length   247 a.a.
NCBI ID   WP_000660575.1    Uniprot ID   E8QTP0
Organism   Helicobacter pylori SouthAfrica7     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 33215..43958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSA_RS00185 (HPSA_00160) panD 35370..35720 (+) 351 WP_000142294.1 aspartate 1-decarboxylase -
  HPSA_RS00190 (HPSA_00165) - 35731..36024 (+) 294 WP_000347932.1 YbaB/EbfC family nucleoid-associated protein -
  HPSA_RS00195 (HPSA_00170) - 36024..37019 (+) 996 WP_000468493.1 PDZ domain-containing protein -
  HPSA_RS00200 (HPSA_00175) comB6 37025..38089 (+) 1065 WP_014534702.1 P-type conjugative transfer protein TrbL Machinery gene
  HPSA_RS00205 (HPSA_00180) comB7 38105..38218 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  HPSA_RS00210 (HPSA_00185) comB8 38215..38958 (+) 744 WP_000660575.1 type IV secretion system protein Machinery gene
  HPSA_RS00215 (HPSA_00190) comB9 38958..39938 (+) 981 WP_001213934.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPSA_RS00220 (HPSA_00195) comB10 39931..41073 (+) 1143 WP_001045896.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPSA_RS00225 (HPSA_00200) - 41138..42550 (+) 1413 WP_000693966.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPSA_RS00230 (HPSA_00205) gmd 42570..43715 (+) 1146 WP_000659837.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28746.98 Da        Isoelectric Point: 8.9830

>NTDB_id=46808 HPSA_RS00210 WP_000660575.1 38215..38958(+) (comB8) [Helicobacter pylori SouthAfrica7]
MKEKPFNSEQLVFLEELLSHQEKHLENKLSSFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIVFVLAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSNAKVWQRFEDLIKTNNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSITAKLLNENKLVYEKRYKIVMSYVFDAPDFDYASMPKNPTGFKVTRYSITEI
APTSRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=46808 HPSA_RS00210 WP_000660575.1 38215..38958(+) (comB8) [Helicobacter pylori SouthAfrica7]
ATGAAAGAAAAGCCTTTCAACAGCGAGCAGTTAGTCTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTAGTTTTTCAGTGAGCGATTTGGACATGCAAAGCGTGTTTAGGCTGGAGAGGAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGTTTTTGTTTTAGCGATCGTTTTAATCAGCCTCCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAAGATAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCTTTGGCTCGATCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGTATTAATCGCATTGACGATAAGTCGCGCT
ATGAACTGGTGCGCTTGCAAAGCAATGCTAAAGTGTGGCAGCGTTTTGAAGATTTGATTAAAACCAATAACAGCATTTAC
GCGCAAAGCCATTTAGAAAGAGAAGTTCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCAAGCGT
GTCCATTACCGCCAAACTCTTGAATGAAAACAAATTGGTGTATGAAAAGCGTTATAAAATCGTGATGAGTTATGTTTTTG
ACGCTCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAGGTTACTCGTTATAGCATCACTGAAATT
GCACCGACTAGCAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E8QTP0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

92.713

100

0.927

Multiple sequence alignment