NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	I6J92_RS15455	Genome accession	NZ_CP069517
Coordinates	3240876..3242000 (-)	Length	374 a.a.
NCBI ID	WP_000228517.1	Uniprot ID	A0A0H3EME5
Organism	Escherichia coli strain FDAARGOS_1262
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3235876..3247000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J92_RS15425 (I6J92_15425)	yrdA	3237676..3238230 (+)	555	WP_001286206.1	gamma carbonic anhydrase family protein	-
I6J92_RS15430 (I6J92_15430)	yrdB	3238206..3238463 (-)	258	WP_001070563.1	DUF1488 domain-containing protein	-
I6J92_RS15435 (I6J92_15435)	aroE	3238460..3239278 (-)	819	WP_000451249.1	shikimate dehydrogenase	-
I6J92_RS15440 (I6J92_15440)	tsaC	3239283..3239855 (-)	573	WP_001468260.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
I6J92_RS15445 (I6J92_15445)	yrdD	3239860..3240402 (-)	543	WP_001312137.1	type I DNA topoisomerase	-
I6J92_RS15450 (I6J92_15450)	smg	3240431..3240904 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
I6J92_RS15455 (I6J92_15455)	dprA	3240876..3242000 (-)	1125	WP_000228517.1	DNA-protecting protein DprA	Machinery gene
I6J92_RS15460 (I6J92_15460)	def	3242130..3242639 (+)	510	WP_000114984.1	peptide deformylase	-
I6J92_RS15465 (I6J92_15465)	fmt	3242654..3243601 (+)	948	WP_000004425.1	methionyl-tRNA formyltransferase	-
I6J92_RS15470 (I6J92_15470)	rsmB	3243653..3244942 (+)	1290	WP_000744773.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
I6J92_RS15475 (I6J92_15475)	trkA	3244964..3246340 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
I6J92_RS15480 (I6J92_15480)	mscL	3246470..3246883 (+)	414	WP_000022450.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40910.86 Da Isoelectric Point: 6.0395

                                >NTDB_id=467699 I6J92_RS15455 WP_000228517.1 3240876..3242000(-) (dprA) [Escherichia coli strain FDAARGOS_1262]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=467699 I6J92_RS15455 WP_000228517.1 3240876..3242000(-) (dprA) [Escherichia coli strain FDAARGOS_1262]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT

TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGCCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0H3EME5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.78	98.663	0.481
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.355	82.888	0.409
dprA	Vibrio cholerae strain A1552	49.355	82.888	0.409
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	44.242	88.235	0.39

Detailed information NTG0467699