NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	I6J98_RS20405	Genome accession	NZ_CP069501
Coordinates	4294071..4295195 (-)	Length	374 a.a.
NCBI ID	WP_000228525.1	Uniprot ID	-
Organism	Escherichia coli strain FDAARGOS_1268
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4289071..4300195

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J98_RS20375 (I6J98_20370)	yrdA	4290871..4291425 (+)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
I6J98_RS20380 (I6J98_20375)	yrdB	4291401..4291658 (-)	258	WP_001070584.1	DUF1488 domain-containing protein	-
I6J98_RS20385 (I6J98_20380)	aroE	4291655..4292473 (-)	819	WP_063624897.1	shikimate dehydrogenase	-
I6J98_RS20390 (I6J98_20385)	tsaC	4292478..4293050 (-)	573	WP_001361937.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
I6J98_RS20395 (I6J98_20390)	yrdD	4293055..4293597 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
I6J98_RS20400 (I6J98_20395)	smg	4293626..4294099 (-)	474	WP_000460682.1	DUF494 family protein Smg	-
I6J98_RS20405 (I6J98_20400)	dprA	4294071..4295195 (-)	1125	WP_000228525.1	DNA-protecting protein DprA	Machinery gene
I6J98_RS20410 (I6J98_20405)	def	4295325..4295834 (+)	510	WP_000114986.1	peptide deformylase	-
I6J98_RS20415 (I6J98_20410)	fmt	4295849..4296796 (+)	948	WP_000004466.1	methionyl-tRNA formyltransferase	-
I6J98_RS20420 (I6J98_20415)	rsmB	4296842..4298131 (+)	1290	WP_001361938.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
I6J98_RS20425 (I6J98_20420)	trkA	4298153..4299529 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
I6J98_RS20430 (I6J98_20425)	mscL	4299659..4300069 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40933.83 Da Isoelectric Point: 6.1402

                                >NTDB_id=467634 I6J98_RS20405 WP_000228525.1 4294071..4295195(-) (dprA) [Escherichia coli strain FDAARGOS_1268]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHAPLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=467634 I6J98_RS20405 WP_000228525.1 4294071..4295195(-) (dprA) [Escherichia coli strain FDAARGOS_1268]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCTCCACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Legionella pneumophila strain ERS1305867	43.363	90.642	0.393
dprA	Haemophilus influenzae Rd KW20	43.62	90.107	0.393

Detailed information NTG0467634