Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   HPCU_RS00200 Genome accession   NC_017358
Coordinates   35419..36555 (+) Length   378 a.a.
NCBI ID   WP_001045874.1    Uniprot ID   A0AB32X5Y6
Organism   Helicobacter pylori Cuz20     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 30419..41555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPCU_RS00170 (HPCU_00155) panD 30859..31209 (+) 351 WP_000142269.1 aspartate 1-decarboxylase -
  HPCU_RS00175 (HPCU_00160) - 31220..31522 (+) 303 WP_000347918.1 YbaB/EbfC family nucleoid-associated protein -
  HPCU_RS00180 (HPCU_00165) - 31522..32529 (+) 1008 WP_000468455.1 PDZ domain-containing protein -
  HPCU_RS00185 (HPCU_00170) comB6 32537..33592 (+) 1056 WP_000786664.1 P-type conjugative transfer protein TrbL Machinery gene
  HPCU_RS07965 comB7 33608..33721 (+) 114 WP_001217864.1 hypothetical protein Machinery gene
  HPCU_RS00190 (HPCU_00175) comB8 33718..34461 (+) 744 WP_000660504.1 type IV secretion system protein Machinery gene
  HPCU_RS00195 (HPCU_00180) comB9 34461..35426 (+) 966 WP_014534167.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPCU_RS00200 (HPCU_00185) comB10 35419..36555 (+) 1137 WP_001045874.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPCU_RS00205 (HPCU_00190) - 36625..38037 (+) 1413 WP_000694823.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPCU_RS00210 (HPCU_00195) gmd 38052..39197 (+) 1146 WP_000659884.1 GDP-mannose 4,6-dehydratase -
  HPCU_RS00215 (HPCU_00200) - 39190..40122 (+) 933 WP_001002523.1 GDP-L-fucose synthase family protein -
  HPCU_RS00220 (HPCU_00205) hypE 40425..41423 (-) 999 WP_000378806.1 hydrogenase expression/formation protein HypE -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 42062.70 Da        Isoelectric Point: 9.9924

>NTDB_id=46747 HPCU_RS00200 WP_001045874.1 35419..36555(+) (comB10) [Helicobacter pylori Cuz20]
MNKWLKGALVFVGGFATIVTISLIYHQKPKAPLNNQPNLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNSSKEETFKSPPIDLKANTTPPKKDFSLKQLDLLAARITPFKQSPKNYEENLIFPMDNPKGIDGFTNLKE
KDIATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFASMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEGATNFFGDYLLMQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=46747 HPCU_RS00200 WP_001045874.1 35419..36555(+) (comB10) [Helicobacter pylori Cuz20]
ATGAATAAGTGGCTTAAGGGGGCGCTTGTTTTTGTAGGGGGTTTTGCAACGATTGTAACAATTTCTTTAATCTATCATCA
AAAGCCAAAAGCCCCCCTAAATAACCAACCCAACCTTTTGAATGACGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACTCAAAACCCACAGCCAACTAACACAGAAAGCTCCAAAGACGCTACCATCAAAGCCTTACAAGAACAGCTAAAAGCC
GCCTTAAAAGCCCTAAACTCCAAAGAAATGAACTCTTCTAAAGAAGAAACTTTTAAGAGCCCTCCCATAGATTTAAAAGC
AAACACAACCCCCCCTAAAAAAGACTTTTCTTTAAAGCAATTAGATTTACTAGCCGCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTCCCCATGGATAACCCTAAGGGTATTGATGGTTTTACCAACCTTAAAGAA
AAAGACATCGCCACCAATGAAAACAAGCTTTTACGCACCATTACAGCCGATAAAATGATACCCGCCTTTTTGATCACGCC
TATTTCTAGCCAGATCGCTGGTAAAGTCATCGCGCAAGTGGAAAGCGATATTTTTGCGAGCATGGGCAAGGCCGTCTTAA
TCCCCAAAGGCTCTAAAGTCATAGGTTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGC
CGCATCATCACCCCCCATGGCATCAATATCATGCTCACTAACGCTAAAGGGGCGGACATTAAAGGCTATAACGGCTTGGT
GGGGGAATTGATTGAAAGGAATTTCCAACGCTATGGCGTGCCGTTACTGCTTTCTACGCTCACTAACGGCTTGTTGATTG
GGATCACTTCGGCTTTAAACAACAGGGGCAATAAAGAAGGAGCCACCAATTTCTTTGGGGATTATCTTTTAATGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGATAAGAGCAAAATCGCTCCTATTGTGGT
GATTAGAGAGGGAAGTAGGGTCTTCATTTCGCCCAATACTGACATCTTCTTTCCTATACCCAGAGAGAATGAAGTCATCG
CTGAGTTTTTAAAATAA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(173-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

96.825

100

0.968

Multiple sequence alignment