Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPCU_RS00190 Genome accession   NC_017358
Coordinates   33718..34461 (+) Length   247 a.a.
NCBI ID   WP_000660504.1    Uniprot ID   A0AB32X630
Organism   Helicobacter pylori Cuz20     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 28718..39461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPCU_RS00170 (HPCU_00155) panD 30859..31209 (+) 351 WP_000142269.1 aspartate 1-decarboxylase -
  HPCU_RS00175 (HPCU_00160) - 31220..31522 (+) 303 WP_000347918.1 YbaB/EbfC family nucleoid-associated protein -
  HPCU_RS00180 (HPCU_00165) - 31522..32529 (+) 1008 WP_000468455.1 PDZ domain-containing protein -
  HPCU_RS00185 (HPCU_00170) comB6 32537..33592 (+) 1056 WP_000786664.1 P-type conjugative transfer protein TrbL Machinery gene
  HPCU_RS07965 comB7 33608..33721 (+) 114 WP_001217864.1 hypothetical protein Machinery gene
  HPCU_RS00190 (HPCU_00175) comB8 33718..34461 (+) 744 WP_000660504.1 type IV secretion system protein Machinery gene
  HPCU_RS00195 (HPCU_00180) comB9 34461..35426 (+) 966 WP_014534167.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPCU_RS00200 (HPCU_00185) comB10 35419..36555 (+) 1137 WP_001045874.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPCU_RS00205 (HPCU_00190) - 36625..38037 (+) 1413 WP_000694823.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPCU_RS00210 (HPCU_00195) gmd 38052..39197 (+) 1146 WP_000659884.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28585.78 Da        Isoelectric Point: 8.9830

>NTDB_id=46745 HPCU_RS00190 WP_000660504.1 33718..34461(+) (comB8) [Helicobacter pylori Cuz20]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=46745 HPCU_RS00190 WP_000660504.1 33718..34461(+) (comB8) [Helicobacter pylori Cuz20]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGTTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACAGGGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCAGCTAAACTCATGAATGAAAACAAGCTAGTTTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment