Detailed information NTG0464807

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: S9968_RS00705
• Genome accession: NZ_CP058666
• Coordinates: 115298..116371 (-)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain S9968
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 110298..121371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S9968_RS00685 (S9968_100138)	-	111572..112087 (-)	516	WP_000919802.1	VanZ family protein	-
S9968_RS00690 (S9968_100139)	rlmN	112087..113193 (-)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
S9968_RS00695 (S9968_100140)	-	113244..113822 (-)	579	WP_001224500.1	YutD-like domain-containing protein	-
S9968_RS00700	-	113891..115223 (-)	1333	Protein_140	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
S9968_RS00705 (S9968_100143)	sepM	115298..116371 (-)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
S9968_RS00710 (S9968_100144)	coaD	116361..116846 (-)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
S9968_RS00715 (S9968_100145)	-	116843..117133 (-)	291	WP_000384889.1	hypothetical protein	-
S9968_RS00720 (S9968_100146)	rsmD	117145..117684 (-)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
S9968_RS00725 (S9968_100147)	-	117814..118263 (+)	450	WP_000592263.1	thiol reductase thioredoxin	-
S9968_RS00730 (S9968_100148)	asnA	118308..119300 (-)	993	WP_000748011.1	aspartate--ammonia ligase	-
S9968_RS00735 (S9968_100149)	-	119414..120478 (-)	1065	WP_000021302.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=464807 S9968_RS00705 WP_000796095.1 115298..116371(-) (sepM) [Streptococcus agalactiae strain S9968]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=464807 S9968_RS00705 WP_000796095.1 115298..116371(-) (sepM) [Streptococcus agalactiae strain S9968]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658