Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   HMPREF0772_RS08565 Genome accession   NC_017342
Coordinates   1693275..1694249 (+) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus subsp. aureus TCH60     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1688275..1699249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0772_RS08530 (HMPREF0772_11589) rpmG 1688736..1688885 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  HMPREF0772_RS08535 (HMPREF0772_11590) - 1689094..1689633 (+) 540 WP_000164553.1 5-formyltetrahydrofolate cyclo-ligase -
  HMPREF0772_RS08540 (HMPREF0772_11592) - 1689645..1691107 (+) 1463 Protein_1603 rhomboid family intramembrane serine protease -
  HMPREF0772_RS08545 (HMPREF0772_11593) - 1691088..1691291 (+) 204 WP_000087561.1 YqgQ family protein -
  HMPREF0772_RS08550 (HMPREF0772_11594) - 1691288..1692274 (+) 987 WP_000161314.1 ROK family glucokinase -
  HMPREF0772_RS08555 (HMPREF0772_11595) - 1692274..1692603 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  HMPREF0772_RS08560 (HMPREF0772_11596) - 1692600..1693223 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  HMPREF0772_RS08565 (HMPREF0772_11597) comGA 1693275..1694249 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF0772_RS08570 (HMPREF0772_11598) comGB 1694221..1695291 (+) 1071 WP_000776412.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF0772_RS08575 (HMPREF0772_11599) comGC 1695305..1695616 (+) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  HMPREF0772_RS08580 (HMPREF0772_11600) comGD 1695594..1696040 (+) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF0772_RS08585 (HMPREF0772_11601) comGE 1696027..1696326 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  HMPREF0772_RS08590 (HMPREF0772_11602) comGF 1696244..1696741 (+) 498 WP_001799534.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF0772_RS08595 - 1696838..1696984 (+) 147 WP_001789879.1 hypothetical protein -
  HMPREF0772_RS08600 (HMPREF0772_11603) - 1696974..1697498 (+) 525 WP_001015125.1 shikimate kinase -
  HMPREF0772_RS08605 (HMPREF0772_11604) gcvT 1697657..1698748 (+) 1092 WP_000093347.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=46474 HMPREF0772_RS08565 WP_000697220.1 1693275..1694249(+) (comGA) [Staphylococcus aureus subsp. aureus TCH60]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=46474 HMPREF0772_RS08565 WP_000697220.1 1693275..1694249(+) (comGA) [Staphylococcus aureus subsp. aureus TCH60]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTGCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment