Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HW271_RS06205 Genome accession   NZ_CP058258
Coordinates   1270349..1271086 (-) Length   245 a.a.
NCBI ID   WP_178895292.1    Uniprot ID   A0A7H8Z944
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1265349..1276086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS06200 (HW271_06200) - 1269640..1270203 (-) 564 WP_178895291.1 TIGR01440 family protein -
  HW271_RS06205 (HW271_06205) mecA 1270349..1271086 (-) 738 WP_178895292.1 adaptor protein MecA Regulator
  HW271_RS06210 (HW271_06210) - 1271211..1272689 (+) 1479 WP_178895293.1 oligosaccharide flippase family protein -
  HW271_RS06215 (HW271_06215) - 1272834..1273820 (+) 987 WP_220428597.1 ComEC/Rec2 family competence protein -
  HW271_RS08745 - 1273769..1274194 (+) 426 WP_220428598.1 hypothetical protein -
  HW271_RS06220 (HW271_06220) - 1274249..1274971 (-) 723 WP_178895294.1 LicD family protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28440.21 Da        Isoelectric Point: 3.9776

>NTDB_id=463229 HW271_RS06205 WP_178895292.1 1270349..1271086(-) (mecA) [Streptococcus sp. oral taxon 061 strain F0704]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLIPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMDELAKMSPDEFLKTLEKTMAEKTKEDIEAIQSLEQVEKEEEASIDEIAEVDEGKREPYIYYILRF
DNLASLVSFAKTVDYQMETSELYKMNDQYYLTVLVDVEDHPSLYPAWLLARMREFADDSDISRSVLQEYGQVIINHDAVQ
GLQKV

Nucleotide


Download         Length: 738 bp        

>NTDB_id=463229 HW271_RS06205 WP_178895292.1 1270349..1271086(-) (mecA) [Streptococcus sp. oral taxon 061 strain F0704]
ATGAAAATGAAACAAATCAGTGATACGACTTTAAAAATCACGATGTCTTTAGAAGATTTGATGGATCGTGGAATGGAAAT
CGCAGACTTTCTCATTCCACAGGAAAAAACAGAAGAGTTTTTCTATGCAATCTTGGATGAGTTAGAAATGCCAGACAGCT
TTTTGGATACAGGAATGCTTAGCTTCCGAGTGACACCGAAGCCTGATAAGGTTGATGTCTTTGTGACCAAGTCTAAGATT
GACCAAAACTTGGATTTTGAAGATTTGGCAGATCTTCCAGATATGGATGAGTTAGCGAAAATGTCTCCAGATGAATTTTT
GAAGACTTTGGAGAAAACCATGGCAGAGAAAACTAAAGAGGATATTGAAGCCATTCAATCTTTAGAGCAGGTTGAAAAAG
AAGAGGAAGCATCAATTGATGAAATTGCTGAGGTGGATGAAGGGAAAAGAGAACCTTATATCTACTACATCTTACGTTTT
GACAACCTAGCTAGTTTAGTTTCTTTTGCTAAAACGGTTGATTACCAAATGGAGACTTCAGAACTCTACAAGATGAATGA
CCAATACTATCTAACAGTTTTGGTTGATGTAGAGGATCATCCAAGTCTTTATCCAGCATGGTTATTGGCACGTATGCGCG
AATTTGCGGATGATAGTGATATCAGTCGCTCAGTCCTTCAAGAATATGGACAAGTCATCATCAATCATGATGCTGTTCAA
GGACTTCAAAAGGTCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8Z944

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

82.041

100

0.82
  mecA Streptococcus pneumoniae D39

82.041

100

0.82
  mecA Streptococcus pneumoniae R6

82.041

100

0.82
  mecA Streptococcus pneumoniae TIGR4

82.041

100

0.82
  mecA Streptococcus mutans UA159

52.846

100

0.531
  mecA Streptococcus thermophilus LMD-9

46.988

100

0.478
  mecA Streptococcus thermophilus LMG 18311

46.586

100

0.473