Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   HW271_RS02245 Genome accession   NZ_CP058258
Coordinates   454128..455978 (+) Length   616 a.a.
NCBI ID   WP_178894685.1    Uniprot ID   A0A7H8Z6D4
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 449128..460978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS02230 (HW271_02230) fmt 451137..452072 (+) 936 WP_178894682.1 methionyl-tRNA formyltransferase -
  HW271_RS02235 (HW271_02235) rsmB 452065..453378 (+) 1314 WP_178894683.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  HW271_RS02240 (HW271_02240) - 453394..454131 (+) 738 WP_178894684.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HW271_RS02245 (HW271_02245) stkP 454128..455978 (+) 1851 WP_178894685.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  HW271_RS02250 (HW271_02250) - 456079..456837 (+) 759 WP_178894686.1 threonine/serine exporter family protein -
  HW271_RS02255 (HW271_02255) - 456839..457288 (+) 450 WP_178894687.1 threonine/serine exporter family protein -
  HW271_RS02260 (HW271_02260) - 457451..458623 (+) 1173 WP_178894688.1 hydroxymethylglutaryl-CoA synthase -
  HW271_RS02265 (HW271_02265) - 458623..459897 (+) 1275 WP_178894689.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 616 a.a.        Molecular weight: 67854.64 Da        Isoelectric Point: 8.7132

>NTDB_id=463209 HW271_RS02245 WP_178894685.1 454128..455978(+) (stkP) [Streptococcus sp. oral taxon 061 strain F0704]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHAKGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIIFFEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QSLENVVIKATAKKLTDRYQTVSEMYVDLLSSLSYNRRNEPKLVFEDTSKVDTKTLPKISQSTLTGIPKVQPKEESHQSQ
KPTQKATNKETVAKPVKKRRFKARYFVLLASFILVMASLFWIVSKTPATVEIPKVAGQTVAEAKENLKKANFEIGEEKTE
ASDTVEEGRVIRTDPDAGSARKEGTKVNLIISSGQQSFKIGNYIGRKSTDVIAELKGKKVPENLIKIVEEESSETEAGLV
MRQSLPEGTTYDLSKATEITLTVAKKVTSVPMPSYIGSSLEFTKNNLIQIVGVKEANIEVVEVSTAPEGTAEETVVSQSP
KPGEGVDLNTTRIKISIYKPKITTTNPTVSNPSRAETSPQIREPQANQNTTTSDLH

Nucleotide


Download         Length: 1851 bp        

>NTDB_id=463209 HW271_RS02245 WP_178894685.1 454128..455978(+) (stkP) [Streptococcus sp. oral taxon 061 strain F0704]
ATGATCCAGATCGGCAAGATATTTGCCGGACGATATCGGATTATCAAACAAATTGGCCGCGGAGGGATGGCAGATGTCTA
CCTGGCCAAAGATTTGATTCTGGATGGGGAAGAAGTTGCTGTAAAGGTTCTGAGAACCAACTATCAGACAGATCCTATCG
CTGTTGCACGTTTTCAGCGTGAAGCGCGTGCGATGGCAGACTTAGATCATCCTCATATCGTTCGAATTACGGATATCGGT
GAAGAAGACGGTCAGCAGTACCTAGCTATGGAATATGTAGCGGGTCTTGACCTCAAACGCTATATCAAAGAACACTATCC
TCTCTCTAACGAGGAAGCTGTTCGTATCATGGGGCAGATTCTCTTAGCTATGCGTTTGGCACATGCAAAGGGAATTGTTC
ACCGTGATTTGAAACCTCAAAATATTCTCTTGACTCCTGATGGCACTGCAAAAGTTACAGACTTTGGGATTGCGGTGGCC
TTTGCAGAAACAAGTTTGACACAGACCAACTCTATGTTAGGTTCTGTTCACTATCTATCACCTGAACAGGCGCGTGGTTC
AAAGGCGACCATACAGAGTGATATTTATGCCATGGGGATTATTTTCTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GCGATAGTGCTGTTACCATTGCACTTCAGCATTTCCAAAAACCACTTCCTTCTGTCATTGCAGAAAACCCATCAGTGCCA
CAATCCTTGGAAAACGTGGTTATAAAAGCGACAGCTAAAAAGTTAACAGACCGTTACCAAACTGTCTCAGAGATGTATGT
TGATTTATTGAGCAGTCTTTCTTATAACCGTCGCAATGAACCAAAGCTAGTATTTGAAGACACAAGTAAAGTTGATACAA
AAACTTTACCGAAAATCTCACAGTCTACTTTAACAGGGATTCCTAAAGTGCAACCGAAGGAAGAGAGTCATCAGAGCCAA
AAGCCGACCCAAAAGGCAACTAATAAAGAAACCGTTGCAAAACCAGTCAAGAAACGTCGTTTCAAAGCAAGATATTTTGT
GCTTTTAGCTAGTTTTATACTTGTTATGGCTTCTCTATTTTGGATTGTATCGAAAACACCAGCAACTGTGGAAATTCCAA
AAGTTGCAGGACAAACTGTAGCAGAAGCCAAGGAAAATCTTAAAAAAGCTAATTTTGAAATTGGCGAGGAAAAGACTGAA
GCTAGTGATACTGTCGAAGAAGGTCGAGTTATCCGAACAGATCCAGATGCTGGCTCGGCACGAAAAGAAGGAACAAAAGT
TAATCTTATTATCTCTTCAGGTCAGCAATCGTTTAAGATTGGAAATTATATTGGACGTAAATCTACGGACGTCATTGCAG
AATTGAAAGGTAAAAAAGTTCCTGAAAATCTCATCAAGATTGTAGAAGAGGAATCAAGTGAAACAGAGGCGGGCCTTGTT
ATGAGACAGAGTCTGCCAGAAGGAACCACTTATGATCTTAGTAAGGCGACAGAGATTACCTTGACAGTAGCCAAGAAGGT
AACTAGCGTTCCTATGCCAAGTTACATTGGATCAAGTCTTGAATTTACCAAGAATAACTTAATTCAGATAGTAGGTGTAA
AAGAGGCTAATATTGAAGTGGTAGAGGTCTCTACAGCACCAGAGGGAACTGCTGAGGAAACTGTAGTCAGTCAAAGTCCA
AAACCAGGTGAAGGTGTGGATCTGAATACTACTCGTATCAAGATTTCTATCTATAAACCGAAAATAACAACAACAAATCC
TACAGTAAGCAATCCTAGTCGTGCAGAAACATCTCCACAGATTAGAGAACCACAGGCTAATCAAAACACTACAACGTCAG
ATTTGCATTGA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(370-432)

PASTA domain (PASTA)

(439-505)

PASTA domain (PASTA)

(510-579)

Protein kinase domain (Pkinase)

(12-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8Z6D4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

83.559

83.929

0.701
  stkP Streptococcus pneumoniae D39

83.172

83.929

0.698
  stkP Streptococcus pneumoniae R6

83.172

83.929

0.698
  stkP Streptococcus pneumoniae Rx1

82.979

83.929

0.696
  pknB Streptococcus mutans UA159

55.786

93.994

0.524
  stkP/pknB Streptococcus salivarius strain HSISS4

59.754

79.058

0.472