Detailed information NTG0046141

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: LILO_RS11335
• Genome accession: NC_020450
• Coordinates: 2350159..2351160 (-)
• Length: 333 a.a.
• NCBI ID: WP_003131994.1
• Uniprot ID: Q9CDL3
• Organism: Lactococcus lactis subsp. lactis IO-1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2345159..2356160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LILO_RS11310 (lilo_2175)	-	2345484..2345921 (-)	438	WP_015427213.1	low molecular weight protein-tyrosine-phosphatase	-
LILO_RS12145	-	2346065..2346229 (-)	165	WP_021467656.1	hypothetical protein	-
LILO_RS11315 (lilo_2176)	-	2346334..2346930 (-)	597	WP_015427214.1	AAA family ATPase	-
LILO_RS11320 (lilo_2177)	-	2346927..2348045 (-)	1119	WP_225513533.1	ABC transporter permease	-
LILO_RS11325 (lilo_2178)	-	2348350..2348919 (-)	570	WP_015427216.1	hypothetical protein	-
LILO_RS11330 (lilo_2179)	-	2349139..2350023 (-)	885	WP_015427217.1	XRE/MutR family transcriptional regulator	-
LILO_RS11335 (lilo_2180)	ruvB	2350159..2351160 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LILO_RS11340 (lilo_2181)	ruvA	2351287..2351880 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
LILO_RS11345 (lilo_2182)	hexB	2351993..2353963 (-)	1971	WP_042230802.1	DNA mismatch repair endonuclease MutL	Machinery gene
LILO_RS11350 (lilo_2183)	-	2354092..2354787 (-)	696	WP_010906384.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 37633.17 Da
• Isoelectric Point: 4.5825

>NTDB_id=46141 LILO_RS11335 WP_003131994.1 2350159..2351160(-) (ruvB) [Lactococcus lactis subsp. lactis IO-1]
MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGPPGLGKTTMAFVIANELGVNI
KQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVEEVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTR
AGMLSNPLRARFGISSHMEYYQERDLEEIVKRTADIFEVEVIDNAALEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVD
KAITDKALSILDVDAAGLDYIDQKILRTMIEMYHGGPVGIGTLAVNIAEDRETVEDMYEPYLIQKGFLMRTKQGRKVTQR
AYEHLGYVYNEED

Nucleotide

• Length: 1002 bp

>NTDB_id=46141 LILO_RS11335 WP_003131994.1 2350159..2351160(-) (ruvB) [Lactococcus lactis subsp. lactis IO-1]
ATGAACGATATATTAAACAAAGAGCCAATGGAAGAAGATTACGGTATTGAAAAATCTCTACGTCCGCAATTTTTTAATCA
ATATATTGGTCAAGATAAAGTCAAAGAACAATTAGAAATCTTTATTAAAGCAGCAAAAATGCGTGAAGAAGTTTTGGACC
ACGTACTACTTTTTGGTCCTCCGGGACTTGGTAAGACAACAATGGCATTTGTCATTGCCAATGAGTTGGGAGTTAATATT
AAACAAACAGCGGGTCCTGCCATTGAAAAGCCAGGAGATTTAGTTGCAATTTTGAATGAATTGGAACCTGGTGATGTGCT
ATTTATTGATGAAATTCATCGGATGCCAATGCAAGTTGAAGAAGTTCTTTATAGCGCTATGGAAGATTTCTACATTGATA
TTATGCTTGGTTCTGGTGATGGTTCACGCTCGGTTCATTTAGATTTGCCGCCATTTACTCTAGTTGGGGCAACAACAAGA
GCTGGAATGCTTTCTAATCCATTGCGTGCCCGTTTTGGAATTTCAAGTCATATGGAGTATTATCAAGAGCGTGATTTAGA
AGAAATTGTTAAAAGAACAGCTGATATTTTTGAAGTCGAAGTTATTGATAATGCCGCTTTAGAGATTGCTTTACGTAGTC
GAGGGACTCCGCGGATTGCCAATCGTTTACTTAAACGAGTGCGTGATTTTGCTCAAATAATGGGGGATGGCCGAGTGGAT
AAAGCAATTACCGATAAGGCCTTGTCTATTCTTGATGTTGATGCCGCTGGTTTGGATTATATTGACCAAAAAATCCTCCG
CACAATGATTGAAATGTACCACGGTGGTCCTGTTGGGATTGGAACTTTGGCGGTAAATATTGCCGAAGACCGTGAAACGG
TCGAGGATATGTATGAACCTTATTTGATTCAAAAAGGATTTTTGATGAGAACTAAACAGGGACGTAAGGTGACCCAAAGA
GCCTATGAACACCTAGGTTATGTTTACAATGAAGAAGATTGA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: Q9CDL3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	78.614	99.7	0.784
ruvB	Streptococcus pneumoniae D39	78.614	99.7	0.784
ruvB	Streptococcus pneumoniae TIGR4	78.313	99.7	0.781
ruvB	Bacillus subtilis subsp. subtilis str. 168	61.491	96.697	0.595
ruvB	Helicobacter pylori 26695	51.242	96.697	0.495
ruvB	Synechocystis sp. PCC 6803	51.613	93.093	0.48