Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   LILO_RS09750 Genome accession   NC_020450
Coordinates   2045700..2047583 (-) Length   627 a.a.
NCBI ID   WP_015427040.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis IO-1     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 2040700..2052583
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LILO_RS09720 (lilo_1884) - 2041106..2041786 (-) 681 WP_015427034.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  LILO_RS09725 (lilo_1885) macP 2041818..2042096 (-) 279 WP_015427035.1 cell wall synthase accessory phosphoprotein MacP -
  LILO_RS09730 (lilo_1886) - 2042089..2042673 (-) 585 WP_015427036.1 NUDIX hydrolase -
  LILO_RS09735 (lilo_1887) glmU 2042778..2044154 (-) 1377 WP_015427037.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  LILO_RS09740 (lilo_1888) proC 2044382..2045170 (+) 789 WP_015427038.1 pyrroline-5-carboxylate reductase -
  LILO_RS09745 (lilo_1889) rpsO 2045248..2045517 (-) 270 WP_015427039.1 30S ribosomal protein S15 -
  LILO_RS09750 (lilo_1890) pknB 2045700..2047583 (-) 1884 WP_015427040.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  LILO_RS09755 (lilo_1891) - 2047583..2048359 (-) 777 WP_015427041.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  LILO_RS09760 (lilo_1892) rsmB 2048440..2049714 (-) 1275 WP_015427042.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  LILO_RS09765 (lilo_1893) - 2049913..2050419 (-) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  LILO_RS09770 - 2050440..2050628 (-) 189 WP_012898445.1 DUF2273 domain-containing protein -
  LILO_RS09775 (lilo_1894) amaP 2050639..2051199 (-) 561 WP_010906186.1 alkaline shock response membrane anchor protein AmaP -
  LILO_RS09780 (lilo_1895) - 2051227..2051469 (-) 243 WP_015427043.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 67816.83 Da        Isoelectric Point: 4.7347

>NTDB_id=46117 LILO_RS09750 WP_015427040.1 2045700..2047583(-) (pknB) [Lactococcus lactis subsp. lactis IO-1]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEDNDSQTD
EKAASSEVGNKNKKSKKGLIIGLVILLLVVGGATLAWVVSTPTNVKIPNVTNSTLSQAKSKIKDAKLKVGTVHKQQSSTI
AEGNVIKTDPTSGTTVRSNSSVDIYVSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSEKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTSQQADGYVYSVYPTVGA
SVDPTQEIVVTYSVYTAPSSSSTTSESTTTPETSSSTTSSTSSSTTSQPSTDNNNSNKESSTTSSSS

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=46117 LILO_RS09750 WP_015427040.1 2045700..2047583(-) (pknB) [Lactococcus lactis subsp. lactis IO-1]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGCGGCGGAATGGCGAATGTTTA
TCAAGGTGAGGATACTTTTCTTGGTGACCGCTTGGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAATGATGACATCG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGATGTTGGT
GAATTTGAAAGTCAACAATACATTGTTATGGAATTTGTTGACGGCATGACACTTAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACGGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAGGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCAGTTCATTATTTATCACCAGAGCAAGCGCGTGGCTC
AAATGCAACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAGCTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCTGCAGTTGCTATCGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATTAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTCGTCATTAAAGCTACAGCGAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAAACAAAAA
TTATGCCTGCCAATCTAATTAATCCTTATGACACCAAGCCTCTGATTGATAAAAAAGAAGATAATGATTCACAAACAGAT
GAAAAGGCTGCAAGCTCAGAAGTAGGAAATAAAAACAAAAAATCTAAAAAAGGCTTGATTATTGGTCTTGTTATCCTTCT
TTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTCTCAACACCAACTAATGTTAAGATACCTAATGTGACAAACTCGA
CACTTAGCCAAGCAAAAAGCAAAATTAAAGATGCAAAACTTAAAGTAGGAACAGTTCATAAACAACAAAGTTCAACGATT
GCTGAAGGAAATGTTATCAAGACTGATCCAACTAGTGGAACAACCGTGAGATCTAATAGCTCCGTTGATATTTATGTTTC
TACGGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATTGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACTTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGCCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTGAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCGGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCTTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGACCCTCAAGCAACAACGAGTCAACAAGCTGACGGTTATGTATATTCTGTTTATCCGACTGTTGGAGCG
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGCGTCTATACTGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACAACGACGCCTGAAACTTCGTCAAGCACAACTTCAAGTACTTCAAGCTCTACAACAAGTCAGCCGTCAACAGATAACA
ACAATAGCAACAAAGAATCTTCAACAACGTCATCAAGTAGTTGA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(506-573)

PASTA domain (PASTA)

(434-501)

Protein kinase domain (Pkinase)

(12-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

49.081

86.762

0.426
  stkP/pknB Streptococcus salivarius strain HSISS4

51.252

82.775

0.424
  stkP Streptococcus pneumoniae TIGR4

48.024

80.702

0.388
  stkP Streptococcus pneumoniae D39

47.826

80.702

0.386
  stkP Streptococcus pneumoniae R6

47.826

80.702

0.386
  stkP Streptococcus pneumoniae Rx1

47.628

80.702

0.384

Multiple sequence alignment